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- Table of Contents
Facts about Replication protein A 30 kDa subunit.
The aRPA may not promote efficient priming by DNA polymerase alpha but could encourage DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the double incision/excision response of nucleotide excision repair and RAD51-dependent strand exchange. .
Human | |
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Gene Name: | RPA4 |
Uniprot: | Q13156 |
Entrez: | 29935 |
Belongs to: |
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replication factor A protein 2 family |
HSU24186; MGC120333; MGC120334; Replication factor A protein 4; replication protein A 30 kDa subunit; replication protein A complex 34 kd subunit homolog Rpa4; replication protein A4, 30kDa; replication protein A4, 34kDa; RF-A protein 4; RP-A p30
Mass (kDA):
28.868 kDA
Human | |
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Location: | Xq21.33 |
Sequence: | X; NC_000023.11 (96883908..96885467) |
Preferentially expressed in placental and colon mucosa. Widely expressed at intermediate or lower levels.
Nucleus. Localizes to DNA repair foci after DNA damage.
PMID: 7760808 by Keshav K.F., et al. Rpa4, a homolog of the 34-kilodalton subunit of the replication protein A complex.
PMID: 19116208 by Mason A.C., et al. An alternative form of replication protein a prevents viral replication in vitro.