PKN3 Antibodies

AND PKN3 ELISA kits, PKN3 Proteins

Many biological assays use antibodies to detect PKN3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PKN3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PKN3 antibodies...

We validate the specificity of these antibodies to PKN3 by testing them on tissues known to express PKN3 positively and negatively. Browse below to find the PKN3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PKN3 Infographic by Boster Bio

All PKN3 Products

Product

Figures

Specificity

Applications

Price

Anti-PKN3 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A09775
100ul

Anti-PKN beta (PKN3) Mouse Monoclonal Antibody [Clone ID: OTI11D8]

Human

$523
Cat # M09775
100 µl

PKN beta (PKN3) (NM_013355) Human Over-expression Lysate

Human

$628
Cat # LS029941
100 µg

Anti-PKN3 Antibody Picoband™

Human

ELISA, Flow Cytometry, WB

$370
Cat # A09775-1
100 μg/vial

PKN3 Overview

Facts about Serine/threonine-protein kinase N3.

PKN3 3D structure. Source: alphafold

Serine/threonine-protein kinase N3 (PKN3)

Contributes to invasiveness in malignant prostate cancer. .

Gene Information

Human
Gene Name:	PKN3
Uniprot:	Q6P5Z2
Entrez:	29941

Family

Belongs to:

protein kinase superfamily

Alternative Names

EC 2.7.11; EC 2.7.11.13; PKNBETA; protein kinase N3; Protein kinase PKN-beta; Protein-kinase C-related kinase 3; RP11-545E17.1; serine/threonine-protein kinase N3

Molecular Weight

Mass (kDA):
99.421 kDA

Genomic Context


Human

Location:	9q34.11
Sequence:	9; NC_000009.12 (128702497..128720918)

Tissue Specificity

Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.

Subcellular Localizations

Nucleus. Cytoplasm, perinuclear region. Nuclear and perinuclear Golgi region.

Diseases

Neoplasms
Malignant Neoplasms
Neoplasm Metastasis
Prostatic Neoplasms
Metastatic Malignant Neoplasm To The Lymph Node
Cell Invasion
Malignant Neoplasm Of Prostate
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm
Lymphatic Metastasis
Metastatic Malignant Neoplasm To The Lung
Malignant Neoplasm Of Breast

Neoplasm Invasiveness
Malignant Neoplasm Of Lung
Carcinoma
Metastatic Prostate Cancer
Pancreatic Neoplasm
Mammary Neoplasms
Chimera Disorder

Interacting Proteins

ARHGAP10
ARHGAP26
CEP170P1

Pathways

Cell Migration
Rna Interference
Cell Activation
Endothelial Cell Activation
Locomotion
Tube Formation
Cell Growth

Cytokinesis

PTMs

Phosphorylation

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PKN3

References

PMID: 10441506 by Oishi K., et al. Identification and characterization of PKNbeta, a novel isoform of protein kinase PKN: expression and arachidonic acid dependency are different from those of PKNalpha.

PMID: 15282551 by Leenders F., et al. PKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase.