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- Table of Contents
Facts about Serine/threonine-protein kinase N3.
Human | |
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Gene Name: | PKN3 |
Uniprot: | Q6P5Z2 |
Entrez: | 29941 |
Belongs to: |
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protein kinase superfamily |
EC 2.7.11; EC 2.7.11.13; PKNBETA; protein kinase N3; Protein kinase PKN-beta; Protein-kinase C-related kinase 3; RP11-545E17.1; serine/threonine-protein kinase N3
Mass (kDA):
99.421 kDA
Human | |
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Location: | 9q34.11 |
Sequence: | 9; NC_000009.12 (128702497..128720918) |
Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.
Nucleus. Cytoplasm, perinuclear region. Nuclear and perinuclear Golgi region.
PMID: 10441506 by Oishi K., et al. Identification and characterization of PKNbeta, a novel isoform of protein kinase PKN: expression and arachidonic acid dependency are different from those of PKNalpha.
PMID: 15282551 by Leenders F., et al. PKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase.