RNF5 Antibodies

AND RNF5 ELISA kits, RNF5 Proteins

Many biological assays use antibodies to detect RNF5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNF5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNF5 antibodies...

We validate the specificity of these antibodies to RNF5 by testing them on tissues known to express RNF5 positively and negatively. Browse below to find the RNF5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RNF5 Infographic by Boster Bio

All RNF5 Products

Product

Figures

Specificity

Applications

Price

Anti-RNF5 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A05826
100ul

RNF5 (NM_006913) Human Over-expression Lysate

Human

$628
Cat # LS006048
100 µg

RNF5 Overview

Facts about E3 ubiquitin-protein ligase RNF5.

RNF5 3D structure. Source: alphafold

E3 ubiquitin-protein ligase RNF5 (RNF5)

Has E2-dependent E3 ubiquitin-protein ligase activity. May work together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4.

Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin.

Gene Information

Human
Gene Name:	RNF5
Uniprot:	Q99942
Entrez:	6048

Family

Belongs to:

No superfamily

Alternative Names

EC 6.3.2.-; G16; HsRma1; NG2; Protein G16; ring finger protein 5Ram1 homolog; RING5hsRma1; RMA1E3 ubiquitin-protein ligase RNF5

Molecular Weight

Mass (kDA):
19.881 kDA

Genomic Context


Human

Location:	6p21.32
Sequence:	6; NC_000006.12 (32178405..32180793)

Subcellular Localizations

Membrane; Multi-pass membrane protein. Mitochondrion membrane. Endoplasmic reticulum membrane. Predominantly located in the plasma membrane, with some localization occurring within cytoplasmic organelles.

Diseases

Cystic Fibrosis
Fibrosis
Neoplasms
Tissue Adhesions
Virus Diseases
Sting Injury
Melanoma
Tumor Progression
Malignant Neoplasm Of Breast
Parkinson Disease
Endoplasmic Reticulum Stress
Myopathy

Malignant Neoplasms
Secondary Parkinson Disease
Mammary Neoplasms
Myositis
Bacterial Infections
Streptococcal Infections
Abnormal Degeneration

Interacting Proteins

ABHD16A
CFTR
CYB561
CYB561A3
INSIG2

PXN
RNF185
SEC22A
SLC1A1
SLC1A5

SLC38A2
SLC38A7
TMEM242
UBE2D1
UBE2D2

UBE2D3
UBE2D4
UBE2E2
UBE2E3
UBE2K

UBE2W
YIPF2

Pathways

Cell Adhesion
Cell Migration
Cell Proliferation
Response To Stress
Localization
Regeneration
Mitochondrial Translocation
Translation
Cell Death
Cell Motility

Cell Differentiation
Proteasome Assembly
Mrna Processing
Pathogenesis
Autophagy

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RNF5

References

PMID: 9533025 by Kyushiki H., et al. Cloning, expression and mapping of a novel RING-finger gene (RNF5), a human homologue of a putative zinc-finger gene from Caenorhabditis elegans.

PMID: 11329381 by Matsuda N., et al. Rma1, a novel type of RING finger protein conserved from Arabidopsis to human, is a membrane-bound ubiquitin ligase.