RNF41 Antibodies

AND RNF41 ELISA kits, RNF41 Proteins

Many biological assays use antibodies to detect RNF41, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNF41 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNF41 antibodies...

We validate the specificity of these antibodies to RNF41 by testing them on tissues known to express RNF41 positively and negatively. Browse below to find the RNF41 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RNF41 Infographic by Boster Bio

All RNF41 Products

Product

Figures

Specificity

Applications

Price

Anti-NRDP1 (E119) RNF41 Antibody

Human, Mouse, Rat

$405
Cat # A04669
100ul

Anti-RNF41 Mouse Monoclonal Antibody [Clone ID: OTI2C1]

Human, Mouse, Rat

$523
Cat # M04669
100 µl

RNF41 (NM_005785) Human Over-expression Lysate

Human

$628
Cat # LS010193
100 µg

RNF41 Overview

Facts about E3 ubiquitin-protein ligase NRDP1.

RNF41 3D structure. Source: alphafold

E3 ubiquitin-protein ligase NRDP1 (RNF41)

Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins. Polyubiquitinates MYD88.

Negatively regulates MYD88-dependent production of proinflammatory cytokines. Can encourage TRIF-dependent creation of type I interferon and inhibits infection with vesicular stomatitis virus (By similarity).

Gene Information

Human
Gene Name:	RNF41
Uniprot:	Q9H4P4
Entrez:	10193

Family

Belongs to:

No superfamily

Alternative Names

E3 ubiquitin-protein ligase NRDP1; EC 6.3.2; EC 6.3.2.-; FLRF; MGC45228; NRDP1; ring finger protein 41neuregulin receptor degradation protein-1; SBBI03

Molecular Weight

Mass (kDA):
35.905 kDA

Genomic Context


Human

Location:	12q13.3
Sequence:	12; NC_000012.12 (56202179..56221982, complement)

Tissue Specificity

Detected in ovary, testis and prostate.

Diseases

Malignant Neoplasms
Neoplasms
Mammary Neoplasms
Parkinson Disease
Malignant Neoplasm Of Breast
Leukemia
Inflammation
Tumor Progression
Animal Mammary Neoplasms
Cell Transformation, Neoplastic
Infectious Mononucleosis

Neoplasms, Hormone-dependent
Myeloid Leukemia
Lymphoma
Hematologic Neoplasms
Anxiety Disorders
Ischemia

Interacting Proteins

ASB6
C1orf109
ENOPH1
HOMER2
ISCA2

LZTS2
N4BP3
RFC4
RRM2B
SRR

TTC1
VPS52

Pathways

Cell Growth
Pathogenesis
Immune Response
Cell Cycle
Transport
Cell Proliferation
Localization
Hematopoietic Progenitor Cell Differentiation
Macrophage Activation
Protein Destabilization
Interferon-beta Production

Dna Replication
Cell Death
Cell Differentiation
Rna Interference
Autophagy

PTMs

Ubiquitination

Phosphorylation

Cleavage

Research Areas

Zinc Finger

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RNF41

References

PMID: 12411582 by Qiu X.-B., et al. Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3.

PMID: 14765125 by Qiu X.B., et al. Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis.