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RNF114 Antibodies

AND RNF114 ELISA kits, RNF114 Proteins

Many biological assays use antibodies to detect RNF114, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNF114 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNF114 antibodies...

We validate the specificity of these antibodies to RNF114 by testing them on tissues known to express RNF114 positively and negatively. Browse below to find the RNF114 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RNF114 Infographic by Boster Bio

RNF114 protein infographic

All RNF114 Products

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Product

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Specificity

Applications

Price

Human RNF114 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTQ9Y508
Starting from 20ug

ZNF313 (RNF114) (NM_018683) Human Over-expression Lysate

Human

$628
Cat # LS055905
100 µg

RNF114 Overview

Facts about E3 ubiquitin-protein ligase RNF114.

RNF114 3D structure

RNF114 3D structure. Source: alphafold

E3 ubiquitin-protein ligase RNF114 (RNF114)

E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and curb cellular senescence.

May play a role in spermatogenesis. .

Gene Information

Human
Gene Name:	RNF114
Uniprot:	Q9Y508
Entrez:	55905

Gene Information

Family

Belongs to:

No superfamily

Family

Alternative Names

ring finger protein 114; Zinc finger protein 228; Zinc finger protein 313ZNF313PSORS12; ZNF228

Molecular Weight

Mass (kDA):
25.694 kDA

Molecular Weight

Genomic Context


Human

Location:	20q13.13
Sequence:	20; NC_000020.11 (49936397..49953885)

Tissue Specificity

Expressed in numerous tissues, including skin, CD4 lymphocytes and dendritic cells. Highest levels in testis.

Subcellular Localizations

Cytoplasm. Nucleus.

Subcellular Localization

Diseases

Psoriasis
Arthritis
Arthritis, Psoriatic
Dermatologic Disorders
Male Infertility
Innate Immune Response
Hiv Infections
Inflammation

Oligospermia
Dysequilibrium Syndrome

Disease

Pathways

Spermatogenesis
Cytokine Production
Pathogenesis

Pathways

PTMs

Ubiquitination

Myristoylation

Research Areas

Zinc Finger

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RNF114

References

PMID: 12621547 by Ma Y.-X., et al. Identification of a novel human zinc finger protein gene ZNF313.

PMID: 18364390 by Capon F., et al. Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene.