RNF113A Antibodies

AND RNF113A ELISA kits, RNF113A Proteins

Many biological assays use antibodies to detect RNF113A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNF113A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNF113A antibodies...

We validate the specificity of these antibodies to RNF113A by testing them on tissues known to express RNF113A positively and negatively. Browse below to find the RNF113A antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RNF113A Infographic by Boster Bio

All RNF113A Products

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RNF113A (NM_006978) Human Recombinant Protein

$813
Cat # PROTO15541
20 µg

RNF113A (NM_006978) Human Over-expression Lysate

Human

$628
Cat # LS007737
100 µg

RNF113A Overview

Facts about E3 ubiquitin-protein ligase RNF113A.

RNF113A 3D structure. Source: alphafold

E3 ubiquitin-protein ligase RNF113A (RNF113A)

E3 ubiquitin-protein ligase that catalyzes the transfer of ubiquitin onto target proteins (PubMed:28978524, PubMed:29144457). Catalyzes polyubiquitination of SNRNP200/BRR2 with non-canonical 'Lys-63'-linked polyubiquitin chains (PubMed:29144457).

Plays a role in DNA repair via its role in the synthesis of'Lys-63'-linked polyubiquitin chains that recruit ALKBH3 and the ASCC complex to sites of DNA damage by alkylating agents (PubMed:29144457). Ubiquitinates CXCR4, leading to its degradation, and thereby contributes to the conclusion of CXCR4 signaling (PubMed:28978524).

Gene Information

Human
Gene Name:	RNF113A
Uniprot:	O15541
Entrez:	7737

Family

Belongs to:

No superfamily

Alternative Names

ring finger protein 113A; RNF113Cwc24; zinc finger protein 183 (RING finger, C3HC4 type); Zinc finger protein 183; ZNF183

Molecular Weight

Mass (kDA):
38.787 kDA

Genomic Context


Human

Location:	Xq24
Sequence:	X; NC_000023.11 (119870475..119871733, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Nucleus. Nucleus speckle. Colocalizes with ASCC2 in nuclear foci after DNA damage by alkylating agents. In the absence of DNA damage, colocalizes with the spliceosome components SNRNP200/BRR2 and PRPF8 in nuclear speckles.