RMI2 Antibodies

AND RMI2 ELISA kits, RMI2 Proteins

Many biological assays use antibodies to detect RMI2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RMI2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RMI2 antibodies...

We validate the specificity of these antibodies to RMI2 by testing them on tissues known to express RMI2 positively and negatively. Browse below to find the RMI2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: OSR2

RMI2 Infographic by Boster Bio

All RMI2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-RMI2 Antibody Picoband®

5 Q&As

Human, Mouse, Rat

Flow Cytometry, IHC, IHC-F, ICC, WB

$370
Cat # A08685
100 μg/vial

RMI2 (NM_152308) Human Over-expression Lysate

Human

$628
Cat # LS116028
100 µg

Anti-C16orf75/RMI2 Antibody Picoband®

Human, Mouse, Rat

ELISA, WB

$370
Cat # A08685-1
100 µg/vial

RMI2 Overview

Facts about RecQ-mediated genome instability protein 2.

RMI2 3D structure. Source: alphafold

RecQ-mediated genome instability protein 2 (RMI2)

Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It's required to control sister chromatid segregation and to limit DNA crossover.

Essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM. In the RMI complex, it's required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM.

Gene Information

Human
Gene Name:	RMI2
Uniprot:	Q96E14
Entrez:	116028

Family

Belongs to:

RMI2 family

Alternative Names

BLAP18RMI2; BLM-associated protein of 18 kDa; chromosome 16 open reading frame 75; hRMI2; MGC24665; RecQ-mediated genome instability 2, S. cerevisiae, homolog of; recQ-mediated genome instability protein 2

Molecular Weight

Mass (kDA):
15.865 kDA

Genomic Context


Human

Location:	16p13.13
Sequence:	16; NC_000016.10 (11345438..11351763)

Subcellular Localizations

Nucleus. Colocalizes with BLM at nuclear DNA repair foci.

Diseases

Bloom Syndrome
Genomic Instability
Malignant Neoplasms
Fanconi Anemia
Neoplasms
Cytogenetic Abnormality
Anemia
Malignant Paraganglionic Neoplasm
Instabilities, Chromosomal
Neoplasm Metastasis
Sex Cord-stromal Tumor
Malignant Neoplasm Of Breast

Chromosome Break
Bone Neoplasms
Metastatic Malignant Neoplasm To The Abdominal Cavity
Immunologic Deficiency Syndromes
Osteosarcoma
Endometriosis, Site Unspecified
Fibrosarcoma

Interacting Proteins

RMI1

Pathways

Dna Replication
Chromosome Segregation
Recombinational Repair
Dna Repair
Chromosome Condensation
Localization

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RMI2

References

PMID: 18923082 by Xu D., et al. RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability.

PMID: 18923083 by Singh T.R., et al. BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome.