GTF2A1L Antibodies

AND GTF2A1L ELISA kits, GTF2A1L Proteins

Many biological assays use antibodies to detect GTF2A1L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GTF2A1L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GTF2A1L antibodies...

We validate the specificity of these antibodies to GTF2A1L by testing them on tissues known to express GTF2A1L positively and negatively. Browse below to find the GTF2A1L antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GTF2A1L Infographic by Boster Bio

All GTF2A1L Products

Product

Figures

Specificity

Applications

Price

Anti-ALF (GTF2A1L) Mouse Monoclonal Antibody [Clone ID: OTI1D3]

Human

$523
Cat # M12060
100 µl

ALF (GTF2A1L) (NM_006872) Human Over-expression Lysate

Human

$628
Cat # LS011036
100 µg

GTF2A1L Overview

Facts about TFIIA-alpha and beta-like factor.

GTF2A1L 3D structure. Source: alphafold

TFIIA-alpha and beta-like factor (GTF2A1L)

May serve as a testis specific transcription factor. Binds DNA together with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription.

Gene Information

Human
Gene Name:	GTF2A1L
Uniprot:	Q9UNN4
Entrez:	11036

Family

Belongs to:

TFIIA subunit 1 family

Alternative Names

1-like factor; general transcription factor IIA, 1-like; GTF2A1LF; MGC26254; TFIIA large subunit isoform ALF; TFIIA-alpha and beta-like factor; TFIIA-alpha/beta-like factor

Molecular Weight

Mass (kDA):
52.444 kDA

Genomic Context


Human

Location:	2p16.3
Sequence:	2; NC_000002.12 (48617780..48679609)

Tissue Specificity

Testis specific. Detected in adult testis mostly in round and elongating spermatids (at protein level). Detected in testis.

Subcellular Localizations

Nucleus. Mainly localizes in the annulus and partly in acrosomal cap area of spermatozoa.

Diseases

Leukemia, Experimental
Malignant Neoplasms
Myeloid Leukemia
Neoplasms
Male Infertility
Liver Carcinoma
Precocious Puberty
Leukemia
Pre-eclampsia

Hypogonadism
Infertility
Acute Drug Intoxication

Interacting Proteins

GAB1

Pathways

Methylation
Transport
Secretory Pathway
Dna Replication
Induction Of Apoptosis
Cell Cycle
Vesicle Uncoating
Dna Methylation

Pachytene
Spermatogenesis
Cell Cycle Arrest

PTMs

Cleavage

Methylation

Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GTF2A1L

References

PMID: 10364255 by Upadhyaya A.B., et al. Identification of a general transcription factor TFIIAalpha/beta homolog selectively expressed in testis.

PMID: 16525715 by Huang M., et al. Involvement of ALF in human spermatogenesis and male infertility.