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- Table of Contents
Facts about Inactive rhomboid protein 2.
. .
Human | |
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Gene Name: | RHBDF2 |
Uniprot: | Q6PJF5 |
Entrez: | 79651 |
Belongs to: |
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peptidase S54 family |
FLJ22341; iRHOM2; RHBDF2; RHBDL5; RHBDL5rhomboid family member 2; RHBDL6; rhomboid 5 homolog 2 (Drosophila); Rhomboid 5 homolog 2; rhomboid veinlet-like 5; Rhomboid veinlet-like protein 5; Rhomboid veinlet-like protein 6; rhomboid, veinlet-like 6 (Drosophila); rhomboid, veinlet-like 6; rhomboid-like protein 6; TOCG
Mass (kDA):
96.686 kDA
Human | |
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Location: | 17q25.1 |
Sequence: | 17; NC_000017.11 (76470893..76501440, complement) |
Found in the epidermis and esophageal epithelium.
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane.
PMID: 22265016 by Blaydon D.C., et al. RHBDF2 mutations are associated with tylosis, a familial esophageal cancer syndrome.
PMID: 29897333 by Oikonomidi I., et al. iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.