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- Table of Contents
Facts about Regulator of G-protein signaling 9.
Involved in phototransduction; key component in the recovery phase of visual transduction (By similarity). .
Human | |
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Gene Name: | RGS9 |
Uniprot: | O75916 |
Entrez: | 8787 |
Belongs to: |
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No superfamily |
MGC26458; PERRSMGC111763; regulator of G-protein signaling 9; regulator of G-protein signalling 9; RGS9L
Mass (kDA):
76.966 kDA
Human | |
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Location: | 17q24.1 |
Sequence: | 17; NC_000017.11 (65137370..65227703) |
Highly expressed in the caudate and putamen, lower levels found in the hypothalamus and nucleus accumbens and very low levels in cerebellum. Not expressed in globus pallidus or cingulate cortex. Isoform 2 is expressed predominantly in pineal gland and retina. Isoform 3 is expressed in retina (abundant in photoreceptors).
[Isoform 3]: Membrane; Peripheral membrane protein. Isoform 3 is targeted to the membrane via its interaction with RGS9BP.
PMID: 9765512 by Granneman J.G., et al. Molecular characterization of human and rat RGS9L, a novel splice variant enriched in dopamine target regions, and chromosomal localization of the RGS9 gene.
PMID: 10564809 by Zhang K., et al. Structure, alternative splicing, and expression of the human RGS9 gene.