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- Table of Contents
Facts about Fructose-1,6-bisphosphatase isozyme 2.
Human | |
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Gene Name: | FBP2 |
Uniprot: | O00757 |
Entrez: | 8789 |
Belongs to: |
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FBPase class 1 family |
D-fructose-1,6-bisphosphate 1-phosphohydrolase 2; EC 3.1.3; EC 3.1.3.11; FBPase 2; fructose-1,6-bisphosphatase 2; fructose-1,6-bisphosphatase isozyme 2; hexosediphosphatase; MGC142192; muscle fructose-bisphosphatase
Mass (kDA):
36.743 kDA
Human | |
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Location: | 9q22.32 |
Sequence: | 9; NC_000009.12 (94558720..94593824, complement) |
Expressed in skeletal muscle (at protein level).
Cell junction. Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line. In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca(2+) concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similar
PMID: 9678974 by Tillman H., et al. Isolation and characterization of an allelic cDNA for human muscle fructose-1,6-bisphosphatase.
PMID: 12507293 by Gizak A., et al. Immunohistochemical localization of human fructose-1,6-bisphosphatase in subcellular structures of myocytes.