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- Table of Contents
Facts about Regulator of G-protein signaling 7-binding protein.
When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it's unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cypolasmic shuttling.
Mouse | |
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Gene Name: | Rgs7bp |
Uniprot: | Q8BQP9 |
Entrez: | 52882 |
Belongs to: |
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RGS7BP/RGS9BP family |
R7BP; RGS7BP regulator of G-protein signaling 7 binding protein
Mass (kDA):
29.023 kDA
Mouse | |
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Location: | 13 D1|13 56.9 cM |
Sequence: | 13; |
Specifically expressed in the central nervous system including the retina but not in other non-neuronal tissues (at protein level).
PMID: 15897264 by Drenan R.M., et al. Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family.
PMID: 15632198 by Martemyanov K.A., et al. R7BP, a novel neuronal protein interacting with RGS proteins of the R7 family.