RGS19 Antibodies

AND RGS19 ELISA kits, RGS19 Proteins

Many biological assays use antibodies to detect RGS19, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RGS19 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RGS19 antibodies...

We validate the specificity of these antibodies to RGS19 by testing them on tissues known to express RGS19 positively and negatively. Browse below to find the RGS19 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RGS19 Infographic by Boster Bio

All RGS19 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-RGS19 (phospho-S151) Antibody

Human, Mouse, Rat

$482
Cat # A05669S151
100ul

Anti-RGS19 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A05669
100ul

RGS19 (NM_001039467) Human Recombinant Protein

$813
Cat # PROTP49795
20 µg

RGS19 (NM_005873) Human Over-expression Lysate

Human

$628
Cat # LS010287
100 µg

RGS19 Overview

Facts about Regulator of G-protein signaling 19.

RGS19 3D structure. Source: alphafold

Regulator of G-protein signaling 19 (RGS19)

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, together with the order G(I)a3 > G(I)a1 > G(o)a >> G(z)a/G(I)a2.

Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein. .

Gene Information

Human
Gene Name:	RGS19
Uniprot:	P49795
Entrez:	10287

Family

Belongs to:

No superfamily

Alternative Names

G alpha interacting protein; GAIPG protein signalling regulator 19; G-alpha-interacting protein; GNAI3IP; guanine nucleotide binding protein alpha inhibiting activity polypeptide 3interacting protein; regulator of G-protein signaling 19; regulator of G-protein signalling 19; RGSGAIP

Molecular Weight

Mass (kDA):
24.636 kDA

Genomic Context


Human

Location:	20q13.33
Sequence:	20; NC_000020.11 (64073181..64080004, complement)

Tissue Specificity

Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.

Subcellular Localizations

Membrane; Lipid-anchor.

Diseases

Malignant Neoplasms
Neoplasms
Teratocarcinoma
Malignant Neoplasm Of Stomach
Malignant Neoplasm Of Ovary
Cholangiocarcinoma
Malignant Neoplasm Of Prostate
Cell Transformation, Neoplastic
Heart Failure
Tissue Adhesions
Malignant Neoplasm Of Lung
Carcinoma

Carcinogenesis
Hypertensive Disease
Heart Septal Defects
Retinoblastoma
Colorectal Neoplasms
Headache
Colorectal Cancer

Interacting Proteins

Gnai3

Pathways

Cell Proliferation
Cell Migration
Cell Cycle
Cell Adhesion
Regulation Of Macroautophagy
Lymphocyte Migration
Endocytosis
Localization
Cytokine Production
Macroautophagy

Heart Formation
Translation
Heart Development
Regulation Of Blood Pressure

PTMs

Phosphorylation
Acetylation

Dephosphorylation
Palmitoylation

Research Areas

Autophagy
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RGS19

References

PMID: 8524874 by de Vries L., et al. GAIP, a protein that specifically interacts with the trimeric G protein G alpha i3, is a member of a protein family with a highly conserved core domain.

PMID: 8986788 by de Vries L., et al. GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits.