Regulator of G-protein signaling 16 (RGS16)

Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11602604, PubMed:18434541).

Plays an essential part in the phototransduction cascade by regulating the life and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals (By similarity).