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- Table of Contents
Facts about Regulator of G-protein signaling 16.
Plays an essential part in the phototransduction cascade by regulating the life and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals (By similarity).
Human | |
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Gene Name: | RGS16 |
Uniprot: | O15492 |
Entrez: | 6004 |
Belongs to: |
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No superfamily |
A28-RGS14; A28-RGS14P; hRGS-r; regulator of G-protein signaling 16; regulator of G-protein signalling 16; Retinally abundant regulator of G-protein signaling; Retinal-specific RGS; RGSR; RGS-r
Mass (kDA):
22.749 kDA
Human | |
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Location: | 1q25.3 |
Sequence: | 1; NC_000001.11 (182598623..182604389, complement) |
Abundantly expressed in retina with lower levels of expression in most other tissues.
Membrane; Lipid-anchor.
PMID: 9223279 by Buckbinder L., et al. The p53 tumor suppressor targets a novel regulator of G protein signaling.
PMID: 9469939 by Snow B.E., et al. Cloning of a retinally abundant regulator of G-protein signaling (RGS-r/RGS16): genomic structure and chromosomal localization of the human gene.