RGS12 Antibodies

AND RGS12 ELISA kits, RGS12 Proteins

Many biological assays use antibodies to detect RGS12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RGS12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RGS12 antibodies...

We validate the specificity of these antibodies to RGS12 by testing them on tissues known to express RGS12 positively and negatively. Browse below to find the RGS12 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RGS12 Infographic by Boster Bio

All RGS12 Products

Product

Figures

Specificity

Applications

Price

Anti-RGS12 Antibody

Human, Mouse

$360
Cat # A07317
100 µl

Anti-RGS12 Antibody

3 Q&As

Human, Mouse, Rat

$399
Cat # A07317-1
100μl

Anti-RGS12 Antibody Picoband™

Human, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A07317-2
100 μg/vial

RGS12 (NM_198229) Human Over-expression Lysate

Human

$960
Cat # LS006002
100 µg

RGS12 Overview

Facts about Regulator of G-protein signaling 12.

RGS12 3D structure. Source: alphafold

Regulator of G-protein signaling 12 (RGS12)

Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form.

Gene Information

Human
Gene Name:	RGS12
Uniprot:	O14924
Entrez:	6002

Family

Belongs to:

No superfamily

Alternative Names

DKFZp761K1617; DKFZp761K1817; regulator of G-protein signaling 12; regulator of G-protein signalling 12

Molecular Weight

Mass (kDA):
156.357 kDA

Genomic Context


Human

Location:	4p16.3
Sequence:	4; NC_000004.12 (3292978..3439913)

Tissue Specificity

Isoform 3 is brain specific.

Subcellular Localizations

Nucleus. Cytoplasm. Cell projection, dendrite. Cell junction, synapse.; [Isoform 5]: Nucleus matrix. Also localized to discrete nuclear foci that are distinct from sites of RNA processing, PML nuclear bodies, and PcG domains.

Diseases

Malignant Neoplasms
Neoplasms
Mutation, Out-of-frame
Microsatellite Instability
Adenocarcinoma
Lung Neoplasms
Non-small Cell Lung Carcinoma
Colonic Neoplasms
Malignant Tumor Of Colon
High-frequency Microsatellite Instability
Malignant Neoplasm Of Lung
Carcinogenesis
Retinoblastoma

Colorectal Neoplasms
Aggressive Systemic Mastocytosis
Nervousness
Acute Promyelocytic Leukemia
Giant Cell Tumor Of Bone
Leukemia
Pain

Pathways

Localization
Osteoclast Differentiation
Mitosis
Cell Division
Cell Cycle
Rna Interference
Gene Silencing
Signal Transmission
Metaphase
Ovulation

Asymmetric Cell Division
Dna Replication
Mitotic Spindle Organization
Spindle Organization
Cell Growth

PTMs

Phosphorylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RGS12

References

PMID: 10869340 by Chatterjee T.K., et al. Novel alternative splicing and nuclear localization of human RGS12 gene products.

PMID: 9651375 by Snow B.E., et al. GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain.