RGS1 Antibodies

AND RGS1 ELISA kits, RGS1 Proteins

Many biological assays use antibodies to detect RGS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RGS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RGS1 antibodies...

We validate the specificity of these antibodies to RGS1 by testing them on tissues known to express RGS1 positively and negatively. Browse below to find the RGS1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RGS1 Infographic by Boster Bio

All RGS1 Products

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Specificity

Applications

Price

Anti-RGS1 Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A04483
100ul

Human RGS1 Recombinant Protein

SDS-PAGE

$265
Cat # PROTQ08116
Starting from 20ug

RGS1 Overview

Facts about Regulator of G-protein signaling 1.

RGS1 3D structure. Source: alphafold

Regulator of G-protein signaling 1 (RGS1)

Regulates G protein-coupled receptor signaling cascades, such as signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors (PubMed:10480894). Inhibits B cell chemotaxis toward CXCL12 (By similarity).

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (PubMed:10480894, PubMed:18434541). .

Gene Information

Human
Gene Name:	RGS1
Uniprot:	Q08116
Entrez:	5996

Family

Belongs to:

No superfamily

Alternative Names

1R20Early response protein 1R20; BL34B-cell activation protein BL34; IER1; IR20immediate-early response 1, B-cell specific; regulator of G-protein signaling 1; regulator of G-protein signalling 1

Molecular Weight

Mass (kDA):
23.858 kDA

Genomic Context


Human

Location:	1q31.2
Sequence:	1; NC_000001.11 (192575773..192580024)

Tissue Specificity

Detected in peripheral blood monocytes (PubMed:10480894). Expression is relatively low in B-cells and chronic lymphocytic leukemia B-cells; however, in other types of malignant B-cell such as non-Hodgkin lymphoma and hairy cell leukemia, expression is constitutively high (PubMed:8473738).

Subcellular Localizations

Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.

Diseases

Neoplasms
Malignant Neoplasms
Tissue Adhesions
Celiac Disease
Sclerosis
Carcinoma
Leukemia
Lymphoma
Neoplasm Metastasis
Multiple Sclerosis
Melanoma
Immunologic Deficiency Syndromes
Inflammation

Burkitt Lymphoma
Malignant Paraganglionic Neoplasm
Leukemogenesis
Lymphatic Metastasis
Heart Failure
Diabetes Mellitus
Diabetes Mellitus, Insulin-dependent

Pathways

Cell Migration
Pathogenesis
Chemotaxis
Cell Proliferation
Cell Cycle
Secretion
Cell Activation
Immune Response
Localization
Cell Adhesion
B Cell Activation
Lymphocyte Migration
Cell Growth

Cell Division
Tissue Development
Cell Differentiation
Mating
Transport
Lateral Root Formation
Drought Tolerance

PTMs

Phosphorylation

Methylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RGS1

References

PMID: 8473738 by Hong J.X., et al. Isolation and characterization of a novel B cell activation gene.

PMID: 8241276 by Newton J.S., et al. A B cell specific immediate early human gene is located on chromosome band 1q31 and encodes an alpha helical basic phosphoprotein.