Regucalcin Antibodies

AND RGN ELISA kits, Regucalcin Proteins

Many biological assays use antibodies to detect Regucalcin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Regucalcin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Regucalcin antibodies...

We validate the specificity of these antibodies to Regucalcin by testing them on tissues known to express RGN positively and negatively. Browse below to find the RGN antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RGN Infographic by Boster Bio

All RGN Products

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Product

Figures

Specificity

Applications

Price

Anti-Regucalcin/RGN Antibody Picoband®

4 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # A05900-1
100 μg/vial

Human RGN Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTQ15493
Starting from 20ug

Regucalcin (RGN) (NM_004683) Human Over-expression Lysate

Human

$628
Cat # LS009104
100 µg

RGN Overview

Facts about Regucalcin.

RGN 3D structure. Source: alphafold

Regucalcin (RGN)

Gluconolactonase with low activity towards other sugar lactones, such as gulonolactone and galactonolactone. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro).

Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity).

Gene Information

Human
Gene Name:	RGN
Uniprot:	Q15493
Entrez:	9104

Family

Belongs to:

SMP-30/CGR1 family

Alternative Names

EC 3.1.1.17; gluconolactonase; GNL; RCsenescence marker protein-30; regucalcin (senescence marker protein-30); Senescence marker protein 30; SMP-30; SMP30regucalcin

Molecular Weight

Mass (kDA):
33.253 kDA

Genomic Context


Human

Location:	Xp11.3
Sequence:	X; NC_000023.11 (47078355..47093314)

Subcellular Localizations

Cytoplasm.

Diseases

Liver Carcinoma
Injury To Liver
Ascorbic Acid Deficiency
Liver Regeneration Disorder
Liver Neoplasms
Liver Neoplasms, Experimental
Malignant Neoplasms
Neoplasms
Osteopenia
Drug-induced Liver Injury
Carcinoma
Hemorrhage
Liver Cirrhosis

Stress, Psychological
Hepatitis
Liver Diseases
Insulin Resistance
Fibrosis
Hyperlipidemia
Scurvy

Pathways

Senescence
Aging
Localization
Transport
Cell Proliferation
Cell Death
Translation
Regulation Of Cell Proliferation
Pathogenesis
Bone Resorption
Protein Phosphorylation
Regulation Of Protein Kinase Activity
Regeneration

Secretion
Osteoblast Differentiation
Proteolysis
Spermatogenesis
Cell Cycle
Insulin Secretion
Cell Adhesion

PTMs

Phosphorylation

Dephosphorylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RGN

References

PMID: 7548213 by Fujita T., et al. Isolation of cDNA clone encoding human homologue of senescence marker protein-30 (SMP30) and its location on the X chromosome.

PMID: 10677570 by Misawa H., et al. Transcript heterogeneity of the human gene for Ca2+-binding protein regucalcin.