RFXANK Antibodies

AND RFXANK ELISA kits, RFXANK Proteins

Many biological assays use antibodies to detect RFXANK, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RFXANK in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RFXANK antibodies...

We validate the specificity of these antibodies to RFXANK by testing them on tissues known to express RFXANK positively and negatively. Browse below to find the RFXANK antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RFXANK Infographic by Boster Bio

All RFXANK Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

RFXANK (NM_003721) Human Recombinant Protein

$813
Cat # PROTO14593
20 µg

Anti-RFXANK Mouse Monoclonal Antibody [Clone ID: OTI3E7]

Human, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M07934
100 µl

RFXANK (NM_003721) Human Over-expression Lysate

Human

$628
Cat # LS008625
100 µg

Anti-RFXANK Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A07934
100 µg/vial

RFXANK Overview

Facts about DNA-binding protein RFXANK.

RFXANK 3D structure. Source: alphafold

DNA-binding protein RFXANK (RFXANK)

Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator/CIITA.

May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters (PubMed:9806546, PubMed:10072068, PubMed:10725724).

Gene Information

Human
Gene Name:	RFXANK
Uniprot:	O14593
Entrez:	8625

Family

Belongs to:

No superfamily

Alternative Names

ANKRA1Regulatory factor X subunit B; ankyrin repeat-containing regulatory factor X-associated protein; BLS; DNA-binding protein RFXANK; F14150_1; MGC138628; regulatory factor X-associated ankyrin-containing proteinAnkyrin repeat family A protein 1; RFXB; RFX-BRFX-Bdelta4

Molecular Weight

Mass (kDA):
28.102 kDA

Genomic Context


Human

Location:	19p13.11
Sequence:	19; NC_000019.10 (19192199..19201869)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

Immunologic Deficiency Syndromes
Severe Combined Immunodeficiency
Bare Lymphocyte Syndrome
Congenital Combined Immunodeficiency
Primary Immune Deficiency Disorder
Neoplasms
Infective Disorder
Hereditary Diseases
Autoimmunity
Liver Diseases
Chromosome Break

Malignant Neoplasms
Diarrhea
Protracted Diarrhea
Adenocarcinoma
Graft-vs-host Disease
Acute Gvh Disease

Pathways

Immune Response
Adaptive Immune Response
Histone Deacetylation
Cell Activation
T Cell Activation
Regulation Of Gene Expression
Localization

Nuclear Export

PTMs

Phosphorylation

Deacetylation

Cleavage

Research Areas

Adaptive Immunity
Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RFXANK

References

PMID: 9806546 by Masternak K., et al. A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients.

PMID: 10072068 by Nagarajan U.M., et al. RFX-B is the gene responsible for the most common cause of the bare lymphocyte syndrome, an MHC class II immunodeficiency.