Transcription factor RFX4 Antibodies

AND RFX4 ELISA kits, Transcription factor RFX4 Proteins

Many biological assays use antibodies to detect Transcription factor RFX4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transcription factor RFX4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transcription factor RFX4 antibodies...

We validate the specificity of these antibodies to Transcription factor RFX4 by testing them on tissues known to express RFX4 positively and negatively. Browse below to find the RFX4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RFX4 Infographic by Boster Bio

All RFX4 Products

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Specificity

Applications

Price

RFX4 (NM_032491) Human Over-expression Lysate

Human

$628
Cat # LS005992
100 µg

Anti-RFX4 Antibody Picoband®

Human

ELISA, WB

$370
Cat # A08516-2
100 µg/vial

RFX4 Overview

Facts about Transcription factor RFX4.

RFX4 3D structure. Source: alphafold

Transcription factor RFX4 (RFX4)

Transcription factor that plays a role in early brain development. May activate transcription by interacting directly with the X-box.

May activate transcription from CX3CL1 promoter through the X-box during brain development. .

Gene Information

Human
Gene Name:	RFX4
Uniprot:	Q33E94
Entrez:	5992

Family

Belongs to:

RFX family

Alternative Names

NYD-SP10; Regulatory factor X 4; regulatory factor X, 4 (influences HLA class II expression); regulatory factor X4; Testis development protein NYD-SP10; transcription factor NYD-sp10; transcription factor RFX4

Molecular Weight

Mass (kDA):
83.368 kDA

Genomic Context


Human

Location:	12q23.3
Sequence:	12; NC_000012.12 (106583004..106762803)

Tissue Specificity

Isoform 1: Expressed in brain and gliomas (at protein level). Isoform 2: Testis-specific (at protein level). Isoform 3: Testis-specific (at protein level). Isoform 3: Expressed at a higher level in adult testes and ejaculated spematozoa than in fetal testes. Isoform 4: Testis-specific.

Subcellular Localizations

Nucleus.

Diseases

Hydrocephalus
Congenital Hydrocephalus
Malignant Neoplasms
Bipolar Disorder
Brain Diseases
Neurodegenerative Disorders
Malignant Neoplasm Of Breast
Glioma
Malignant Neoplasm Of Liver
Parkinson Disease
Bare Lymphocyte Syndrome
Edema

Neoplasms
Innate Immune Response
Nervousness
Headache
Situs Inversus
Cell Invasion
Spindle Cell Oncocytoma Of The Adenohypophysis

Pathways

Brain Development
Brain Morphogenesis
Transport
Immune Response
Spermatogenesis
Intraflagellar Transport
Pachytene
Developmental Process
Localization
Humoral Immune Response
Cell Cycle

Axon Guidance
Innate Immune Response
Cell Communication
Forebrain Development
Pathogenesis
Meiosis

PTMs

Biotinylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RFX4

References

PMID: 12925582 by Blackshear P.J., et al. Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4.

PMID: 16271074 by Matsushita H., et al. Identification of glioma-specific RFX4-E and -F isoforms and humoral immune response in patients.