RFC2 Antibodies

AND RFC2 ELISA kits, RFC2 Proteins

Many biological assays use antibodies to detect RFC2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RFC2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RFC2 antibodies...

We validate the specificity of these antibodies to RFC2 by testing them on tissues known to express RFC2 positively and negatively. Browse below to find the RFC2 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RFC2 Infographic by Boster Bio

All RFC2 Products

Product

Figures

Specificity

Applications

Price

Anti-Replication factor C subunit 2 RFC2 Antibody

Human, Mouse, Rat

$405
Cat # A07724
100ul

Anti-RFC2 (T165) Antibody

Human, Mouse, Rat

$405
Cat # A07724T165
100ul

RFC2 (NM_002914) Human Recombinant Protein

$1249
Cat # PROTP35250
20 µg

Anti-RFC2 Mouse Monoclonal Antibody [Clone ID: OTI3A7]

+10

Human, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M07724
100 µl

RFC2 (NM_181471) Human Over-expression Lysate

Human

$628
Cat # LS005982
100 µg

Anti-RFC2 Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A07724-1
100 µg/vial

RFC2 Overview

Facts about Replication factor C subunit 2.

RFC2 3D structure. Source: alphafold

Replication factor C subunit 2 (RFC2)

The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity).

. .

Gene Information

Human
Gene Name:	RFC2
Uniprot:	P35250
Entrez:	5982

Family

Belongs to:

activator 1 small subunits family

Alternative Names

A1 40 kDa subunit; A1; Activator 1 40 kDa subunit; Activator 1 subunit 2; MGC3665; replication factor C (activator 1) 2, 40kDa; replication factor C 2; Replication factor C 40 kDa subunit; replication factor C subunit 2; RF-C 40 kDa subunit; RFC40replication factor C (activator 1) 2 (40kD)

Molecular Weight

Mass (kDA):
39.157 kDA

Genomic Context


Human

Location:	7q11.23
Sequence:	7; NC_000007.14 (74231502..74254458, complement)

Subcellular Localizations

Nucleus.

Diseases

Williams Syndrome
Neoplasms
Carcinoma
Infantile Hypercalcemia
Malignant Paraganglionic Neoplasm
Haploinsufficiency
Carcinogenesis
Cell Transformation, Neoplastic
Glioblastoma
Brain Neoplasms
Hyperplasia
Hypercalcemia

Cholangiocarcinoma
Chronic Myeloid Leukaemia Transformation
Neoplasms, Radiation-induced
Ataxia
Myeloid Leukemia, Chronic
Kidney Neoplasm
Coinfection

Interacting Proteins

PRKAR1A
RFC1
RFC4

Pathways

Dna Replication
Cell Cycle
Dna Damage Checkpoint
Dna Repair
S Phase
Cell Growth
Transport
Nuclear Transport
Cell Division
Cell Proliferation
Mitosis
Localization
Dna Replication Checkpoint

Single-stranded Dna Binding
Dna Integrity Checkpoint
Cell Cycle Checkpoint
Gene Silencing
Proteolysis
Cell Cycle Arrest
Translesion Synthesis

PTMs

Phosphorylation

Research Areas

Cell Cycle and Replication
DNA Repair

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RFC2

References

PMID: 1313560 by Chen M., et al. Sequence and expression in Escherichia coli of the 40-kDa subunit of activator 1 (replication factor C) of HeLa cells.

PMID: 11003705 by Martindale D.W., et al. Comparative genomic sequence analysis of the Williams syndrome region (LIMK1-RFC2) of human chromosome 7q11.23.