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- Table of Contents
Facts about Replication factor C subunit 1.
Binds the PO-B transcription component in addition to other GA rich DNA sequences. Could play a role in DNA transcription regulation in addition to DNA replication and/or repair.
Human | |
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Gene Name: | RFC1 |
Uniprot: | P35251 |
Entrez: | 5981 |
Belongs to: |
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activator 1 large subunit family |
A1 140 kDa subunit; A1; Activator 1 140 kDa subunit; Activator 1 large subunit; Activator 1 subunit 1; MGC51786; MHC binding factor, beta; MHCBFB; PO-GA; RECC1; replication factor C (activator 1) 1 (145kD); replication factor C (activator 1) 1, 145kDa; Replication factor C 140 kDa subunit; Replication factor C large subunit; replication factor C subunit 1; replication factor C1; RF-C 140 kDa subunit; RFC; RFC1; RFC140; RFC140DNA-binding protein PO-GA
Mass (kDA):
128.255 kDA
Human | |
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Location: | 4p14 |
Sequence: | 4; NC_000004.12 (39287456..39366381, complement) |
Wide tissue distribution. Undetectable in placental tissue.
Nucleus.
PMID: 8248204 by Bunz F., et al. cDNAs encoding the large subunit of human replication factor C.
PMID: 8512577 by Lu Y., et al. Cloning and expression of a novel human DNA binding protein, PO-GA.