Renin Antibodies

AND REN ELISA kits, Renin Proteins

Many biological assays use antibodies to detect Renin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Renin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Renin antibodies...

We validate the specificity of these antibodies to Renin by testing them on tissues known to express REN positively and negatively. Browse below to find the REN antibody that suites your experiment. We have 8 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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REN Infographic by Boster Bio

All REN Products

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Product

Figures

Specificity

Applications

Price

Human Renin / Prorenin ELISA Kit PicoKine®

5 Q&As

Human

ELISA

$499
Cat # EK1249
96 wells/kit, with removable strips.

Anti-Renin (L238) Antibody

Human

IHC, WB

$405
Cat # A03689
100ul

Anti-Renin Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A03689-1
100ul

Anti-REN/Renin Antibody

Human

IHC

$370
Cat # A03689-2
100 μg/vial

Human Renin Recombinant Protein

SDS-PAGE

$350
Cat # PROTP00797
Starting from 10ug

Anti-Renin (REN) Mouse Monoclonal Antibody [Clone ID: OTI2F10]

Human

IHC, WB

$523
Cat # M03689
100 µl

Anti-Renin Rabbit Monoclonal Antibody

Human

Flow Cytometry, WB

$370
Cat # M03689-1
100 μl/vial

Anti-Renin/REN Antibody Picoband®

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A03689-3
100 µg/vial

REN Overview

Facts about Renin.

REN 3D structure. Source: alphafold

Renin (REN)

Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, sparking a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. .

Gene Information

Human
Gene Name:	REN
Uniprot:	P00797
Entrez:	5972

Family

Belongs to:

peptidase A1 family

Alternative Names

angiotensin-forming enzyme; Angiotensinogenase; EC 3.4.23; EC 3.4.23.15; FLJ10761; HNFJ2; REN; renin precursor, renal; Renin

Molecular Weight

Mass (kDA):
45.057 kDA

Genomic Context


Human

Location:	1q32.1
Sequence:	1; NC_000001.11 (204154819..204166337, complement)

Subcellular Localizations

Secreted. Membrane. Associated to membranes via binding to ATP6AP2.

Diseases

Hypertensive Disease
Neoplasms
Malignant Neoplasms
Mesothelioma
Malignant Paraganglionic Neoplasm
Kidney Diseases
Essential Hypertension
Malignant Mesothelioma
Cell Transformation, Neoplastic
Pleural Neoplasms
Hypertrophy
Medulloblastoma
Hemorrhage

Carcinoma
Nervousness
Pleural Mesothelioma
Malignant Pleural Mesothelioma
Dysequilibrium Syndrome
Cardiovascular Diseases
Malignant Neoplasm Of Breast

Interacting Proteins

Pathways

Pathogenesis
Localization
Secretion
Transport
Cell Proliferation
Excretion
Cell Death
Oncogenesis
Glycosylation
Ovulation
Aging
Translation
Proprioception

Vasodilation
Detection Of Glucose
Ossification
Tropism
Reflex
Cell Differentiation
Chromatin Remodeling

PTMs

Cleavage
Phosphorylation
Ubiquitination
Glycosylation
Deacetylation
Acetylation

Oxidation
Methylation
Dephosphorylation
Biotinylation
Reduction
Deglycosylation

Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/REN

References

PMID: 6324167 by Imai T., et al. Cloning and sequence analysis of cDNA for human renin precursor.

PMID: 3530608 by Morris B.J.; New possibilities for intracellular renin and inactive renin now that the structure of the human renin gene has been elucidated.