CAAX prenyl protease 2 Antibodies

AND RCE1 ELISA kits, CAAX prenyl protease 2 Proteins

Many biological assays use antibodies to detect CAAX prenyl protease 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CAAX prenyl protease 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CAAX prenyl protease 2 antibodies...

We validate the specificity of these antibodies to CAAX prenyl protease 2 by testing them on tissues known to express RCE1 positively and negatively. Browse below to find the RCE1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RCE1 Infographic by Boster Bio

All RCE1 Products

Product

Figures

Specificity

Applications

Price

Anti-FACE2 RCE1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A06917
100ul

RCE1 (NM_001032279) Human Over-expression Lysate

Human

$628
Cat # LS009986
100 µg

RCE1 Overview

Facts about CAAX prenyl protease 2.

RCE1 3D structure. Source: alphafold

CAAX prenyl protease 2 (RCE1)

Proteolytically removes the C-terminal 3 residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1 (PubMed:10085068).

Gene Information

Human
Gene Name:	RCE1
Uniprot:	Q9Y256
Entrez:	9986

Family

Belongs to:

peptidase U48 family

Alternative Names

CAAX prenyl protease 2; EC 3.4.22.-; FACE-2; FACE2RCE1 homolog, prenyl protein protease (S. cerevisiae); farnesylated protein-converting enzyme 2; Farnesylated proteins-converting enzyme 2; hRCE1; Prenyl protein-specific endoprotease 2; RCE1 (S. Cerevisiae) homolog, prenyl protein protease; RCE1 homolog; RCE1 homolog, prenyl protein peptidase (S. cerevisiae); RCE1 homolog, prenyl protein protease; RCE1A; RCE1B

Molecular Weight

Mass (kDA):
35.833 kDA

Genomic Context


Human

Location:	11q13.2
Sequence:	11; NC_000011.10 (66843441..66846552)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Cell Transformation, Neoplastic
Neoplasms
Progeria
Carcinoma
Lipodystrophy
Myeloproliferative Disease
Cardiomyopathy, Dilated
Cholangiocarcinoma
Malnutrition
Stenosis
Weakness
Familial Generalized Lipodystrophy

Uterine Cervical Neoplasm
Premature Aging Syndrome
Acquired Partial Lipodystrophy
Dysplasia
Fracture
Patient Dependence On
Yersinia Infections

Pathways

Localization
Proteolysis
Prenylation
Methylation
Mating
Cell Proliferation
Protein Prenylation
Conjugation
Cell Growth
Secretion
Protein Processing
Aging
Interphase

Oncogenesis
Transport
Cell Migration
Protein Targeting
Hypersensitivity
Cell Division
Cell Cycle

PTMs

Prenylation
Farnesylation
Cleavage
Methylation

Geranylgeranylation
Phosphorylation
Palmitoylation
Ubiquitination

Biotinylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RCE1

References

PMID: 10373325 by Freije J.M.P., et al. Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins.

PMID: 10085068 by Otto J.C., et al. Cloning and characterization of a mammalian prenyl protein-specific protease.