Calcipressin-1 Antibodies

AND RCAN1 ELISA kits, Calcipressin-1 Proteins

Many biological assays use antibodies to detect Calcipressin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Calcipressin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Calcipressin-1 antibodies...

We validate the specificity of these antibodies to Calcipressin-1 by testing them on tissues known to express RCAN1 positively and negatively. Browse below to find the RCAN1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RCAN1 Infographic by Boster Bio

All RCAN1 Products

Product

Figures

Specificity

Applications

Price

Anti-Calcipressin-1 RCAN1 Antibody

Human, Mouse, Rat

$405
Cat # A02795
100ul

Human DSCR1 isoform b Recombinant Protein

SDS-PAGE

$265
Cat # PROTP53805
Starting from 20ug

Anti-Calcipressin 1 (RCAN1) Mouse Monoclonal Antibody [Clone ID: OTI10C6]

Human, Mouse

$523
Cat # M02795
100 µl

Anti-Calcipressin 1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M02795-1
100 μl/vial

Calcipressin 1 (RCAN1) (NM_203418) Human Over-expression Lysate

Human

$628
Cat # LS001827
100 µg

RCAN1 Overview

Facts about Calcipressin-1.

RCAN1 3D structure. Source: alphafold

Calcipressin-1 (RCAN1)

Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A (PubMed:12809556). Could play a role during central nervous system development (By similarity).

Gene Information

Human
Gene Name:	RCAN1
Uniprot:	P53805
Entrez:	1827

Family

Belongs to:

RCAN family

Alternative Names

ADAPT78; calcipressin-1; calcium and oxidant-inducible mRNA; Down syndrome candidate region 1; Down syndrome critical region gene 1; Down syndrome critical region protein 1; DSC1; modulatory calcineurin-interacting protein 1; Myocyte-enriched calcineurin-interacting protein 1; near DSCR proline-rich protein; regulator of calcineurin 1CSP1DSCR1MCIP1RCN1

Molecular Weight

Mass (kDA):
28.079 kDA

Genomic Context


Human

Location:	21q22.12
Sequence:	21; NC_000021.9 (34516442..34615123, complement)

Tissue Specificity

Highly expressed heart, brain and skeletal muscle. Also expressed in all other tissues.

Diseases

Down Syndrome
Hypertrophy
Alzheimer's Disease
Cardiac Hypertrophy
Tumor Angiogenesis
Trisomy
Neoplasms
Malignant Neoplasms
Inflammation
Heart Failure
Nervousness
Neurofibrillary Tangles

Pathologic Neovascularization
Neuropathology Disease
Congenital Heart Defects
Tissue Adhesions
Neurodegenerative Disorders
Nerve Degeneration

Interacting Proteins

Dyrk1a
RAF1

Pathways

Angiogenesis
Pathogenesis
Localization
Cell Migration
Cell Activation
Cell Proliferation
Hyperphosphorylation
Immune Response
Cell Death
Cell Growth
Secretion
Endothelial Cell Migration
Tube Formation

Cell Adhesion
Aging
Endothelial Cell Proliferation
Translation
Endocytosis
T Cell Activation
Nuclear Export

PTMs

Phosphorylation
Dephosphorylation

Cleavage
Ubiquitination

Oxidation

Research Areas

Cancer
Neuroscience
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RCAN1

References

PMID: 8595418 by Fuentes J.-J., et al. A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart.

PMID: 9325060 by Fuentes J.-J., et al. Genomic organization, alternative splicing, and expression patterns of the DSCR1 (Down syndrome candidate region 1) gene.