RNA-binding protein 5 Antibodies

AND RBM5 ELISA kits, RNA-binding protein 5 Proteins

Many biological assays use antibodies to detect RNA-binding protein 5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNA-binding protein 5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNA-binding protein 5 antibodies...

We validate the specificity of these antibodies to RNA-binding protein 5 by testing them on tissues known to express RBM5 positively and negatively. Browse below to find the RBM5 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RBM5 Infographic by Boster Bio

All RBM5 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-RBM5/Luca15 Antibody

7 Q&As

Human, Mouse

IHC, WB

$360
Cat # A03559
100 µl

RBM5 Colorimetric Cell-Based ELISA

Human, Mouse

ELISA

$480
Cat # EKC1744
1 kit, containing one 96-well plate and all necessary reagents

RBM5 (NM_005778) Human Recombinant Protein

$1249
Cat # PROTP52756
20 µg

RBM5 (NM_005778) Human Over-expression Lysate

Human

$960
Cat # LS010181
100 µg

RBM5 Overview

Facts about RNA-binding protein 5.

RBM5 3D structure. Source: alphafold

RNA-binding protein 5 (RBM5)

Part of the spliceosome A complex.
Regulates alternative splicing of a number of mRNAs.

May modulate splice site pairing following recruitment of the U1 and U2 snRNPs into the 5' and 3' splice sites of the intron. May both positively and negatively regulate apoptosis by regulating the alternative splicing of many genes involved in this process, such as FAS and CASP2/caspase-2.

Gene Information

Human
Gene Name:	RBM5
Uniprot:	P52756
Entrez:	10181

Family

Belongs to:

RBM5/RBM10 family

Alternative Names

G15; H37; LUCA15FLJ39876; Protein G15; Putative tumor suppressor LUCA15; Renal carcinoma antigen NY-REN-9; RMB5; RNA binding motif protein 5; RNA-binding motif protein 5; RNA-binding protein 5

Molecular Weight

Mass (kDA):
92.154 kDA

Genomic Context


Human

Location:	3p21.31
Sequence:	3; NC_000003.12 (50088919..50119021)

Tissue Specificity

Isoform 5 is widely expressed in normal tissues and is expressed at increased levels in T-leukemic cell lines.

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Malignant Neoplasms
Malignant Neoplasm Of Lung
Lung Neoplasms
Non-small Cell Lung Carcinoma
Carcinoma
Mammary Neoplasms
Mutation Abnormality
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Adenocarcinoma
Metastatic Malignant Neoplasm To The Lymph Node

Malignant Neoplasm Of Ovary
Cell Transformation, Neoplastic
Lymphatic Metastasis
Adenocarcinoma Of Lung (disorder)
Stomach Neoplasms
Metastatic Malignant Neoplasm To The Lung
Tumor Progression

Interacting Proteins

DHX15
MEOX1
PRPF19
U2AF2
U2SURP

Pathways

Cell Cycle
Cell Proliferation
Cell Cycle Arrest
Cell Death
Cell Growth
Programmed Cell Death
Reverse Transcription
Cell Adhesion
Gene Silencing
Seed Maturation
G1 Phase

Immune Response
Methylation
Mrna Processing
Pathogenesis
Regulation Of Mrna Processing
Oncogenesis

PTMs

Cleavage
Phosphorylation

Dephosphorylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RBM5

References

PMID: 10486216 by Timmer T., et al. An evolutionary rearrangement of the Xp11.3-11.23 region in 3p21.3, a region frequently deleted in a variety of cancers.

PMID: 10497265 by Oh J.J., et al. Identification of differentially expressed genes associated with HER- 2/neu overexpression in human breast cancer cells.