RNA-binding protein 39 Antibodies

RNA-binding protein 39 (RBM39)

Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing procedure.

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Gene Information

Human
Gene Name:	RBM39
Uniprot:	Q14498
Entrez:	9584

Family

Belongs to:
splicing factor SR family

Alternative Names

CAPER; CC1.3; coactivator of activating protein-1 and estrogen receptors; DKFZp781C0423; FLJ44170; fSAP59; functional spliceosome-associated protein 59; HCC1CAPERalpha; Hepatocellular carcinoma protein 1; RNA binding motif protein 39; RNA-binding motif protein 39; RNA-binding protein 39; RNA-binding region-containing protein 2; RNPC2; RRM) containing 2; splicing factor CC1.3; Splicing factor HCC1

Molecular Weight

Mass (kDA):
59.38 kDA

Genomic Context

Human
Location:	20q11.22
Sequence:	20; NC_000020.11 (35701347..35742336, complement)

Tissue Specificity

Widely expressed. Highly expressed in pancreas, skeletal muscle, lung and brain. Expressed at intermediate level in kidney, liver and heart.

Subcellular Localizations

Nucleus speckle. Concentrated in nuclear speckles. Colocalizes with the core spliceosomal snRNP proteins.

Diseases

• Adenoma
• Carcinoma
• Malignant Neoplasms
• Neoplasms
• Colorectal Neoplasms
• Colorectal Cancer
• Colorectal Adenoma
• Cell Invasion
• Adenocarcinoma
• Cell Transformation, Neoplastic
• Acidosis

• Tumor Progression
• Carcinogenesis
• Myopathy
• Acidosis, Lactic
• Invasive Malignant Neoplasm

Interacting Proteins

• AK8
• BANP
• CLK2
• CSNK2A1
• FAM200A

• GOLGA2
• KHDC4
• KRTAP12-2
• MLX
• NKAPD1

• PCBP1
• PHC2
• PPIG
• REL
• SAP18

• SDCBP
• SF3B4
• SP100
• SREK1IP1
• SRPK1

• SRPK2
• SRSF11
• THAP1
• ZBTB22
• ZCCHC10

Pathways

• Mrna Processing
• Pathogenesis
• Iron-sulfur Cluster Assembly
• Localization

PTMs

• Acetylation
• Isopeptide bond

• Phosphoprotein
• Ubl conjugation

Research Areas

• Cellular Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RBM39

Boster Bio - Best Uses Of The RBM39 Marker

High-affinity primaries antibodies are essential for many purposes, including antibody preparation. Boster offers antibodies with high affinity and good citation numbers. These antibodies have been confirmed in immunohistochemistry or Western Blotting making them a reliable option. This article will discuss the main points of Steven Boster’s life and his work.

Boster has high-affinity prima antibodies

Boster bio high-affinity prima antibodies against RBG39 marker allow scientists to target this tumor-specific protein more precisely. This marker is found in many cancers, such as adrenocortical, cervical squamous, colorectal, colorectal, diffuse large-cell lymphoma (DLB), glioblastoma multiforme and pancreatic cancer.

Highlights of Steven Boster’s career

The RBM39 gene, in addition to being a versatile marker for DNA detection, may also play an important part in many cellular processes. For instance, the gene controls alternative splicing of RNA molecules. By regulating the levels of transcripts, the RBM39 gene may regulate the expression of many different proteins. Below are highlights of Steven Boster’s career using the RBM39 gene marker.