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- Table of Contents
Facts about Ras and EF-hand domain-containing protein.
Binds predominantly GDP, and also GTP.
.Human | |
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Gene Name: | RASEF |
Uniprot: | Q8IZ41 |
Entrez: | 158158 |
Belongs to: |
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small GTPase superfamily |
FLJ31614; RAB45; RAB45, member RAS oncogene family; RAS and EF hand domain containing; RAS and EF-hand domain containing; ras and EF-hand domain-containing protein; Ras-related protein Rab-45
Mass (kDA):
82.879 kDA
Human | |
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Location: | 9q21.32 |
Sequence: | 9; NC_000009.12 (82979589..83063172, complement) |
Down-regulated in cutaneous melanoma cells but not in breast cancer cells.
Cytoplasm, perinuclear region.
PMID: 16174859 by Joensson G., et al. Mapping of a novel ocular and cutaneous malignant melanoma susceptibility locus to chromosome 9q21.32.
PMID: 17448446 by Shintani M., et al. Characterization of Rab45/RASEF containing EF-hand domain and a coiled-coil motif as a self-associating GTPase.