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- Table of Contents
Facts about Rap1 GTPase-activating protein 1.
Human | |
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Gene Name: | RAP1GAP |
Uniprot: | P47736 |
Entrez: | 5909 |
Belongs to: |
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No superfamily |
GTPase activating protein 1; RAP1 GTPase activating protein
Mass (kDA):
73.361 kDA
Human | |
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Location: | 1p36.12 |
Sequence: | 1; NC_000001.11 (21596221..21669444, complement) |
Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues.
Golgi apparatus membrane; Peripheral membrane protein.
PMID: 1904317 by Rubinfeld B., et al. Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1.
PMID: 10476970 by Mochizuki N., et al. Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i).