Ran GTPase-activating protein 1 (RANGAP1)

GTPase activator for RAN (PubMed:8146159, PubMed:8896452, PubMed:16428860).

Converts cytoplasmic GTP-bound RAN into GDP-bound RAN, which is vital for RAN-mediated nuclear import and export (PubMed:8896452, PubMed:27160050).

Mediates dissociation of cargo from nuclear export complexes comprising XPO1, RAN and RANBP2 after nuclear export (PubMed:27160050). .