RAET1E Antibodies

AND RAET1E ELISA kits, RAET1E Proteins

Many biological assays use antibodies to detect RAET1E, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RAET1E in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RAET1E antibodies...

We validate the specificity of these antibodies to RAET1E by testing them on tissues known to express RAET1E positively and negatively. Browse below to find the RAET1E antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RAET1E Infographic by Boster Bio

All RAET1E Products

Product

Figures

Specificity

Applications

Price

Human ULBP-4/RAET1E Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ8TD07
Starting from 4ug

Mouse Rae-1 epsilon Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9CZQ6
Starting from 10ug

ULBP4 (RAET1E) (NM_139165) Human Over-expression Lysate

Human

$628
Cat # LS135250
100 µg

RAET1E Overview

Facts about Retinoic acid early transcript 1E.

RAET1E 3D structure. Source: alphafold

Retinoic acid early transcript 1E (RAET1E)

Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. .

Gene Information

Human
Gene Name:	RAET1E
Uniprot:	Q8TD07
Entrez:	135250

Family

Belongs to:

MHC class I family

Alternative Names

bA350J20.7; LETAL; LETALRAE-1-like transcript 4; Lymphocyte effector toxicity activation ligand; MGC125309; N2DL4; N2DL-4; NKG2D ligand 4; NKG2DL4; RAET1E; RAET1E2; retinoic acid early transcript 1ERL-4; RL-4; ULBP4; ULBP-4; ULBP4MGC125308

Molecular Weight

Mass (kDA):
30.122 kDA

Genomic Context


Human

Location:	6q25.1
Sequence:	6; NC_000006.12 (149864399..149898353, complement)

Tissue Specificity

Predominantly expressed in the skin, but also expressed in testis and trachea. Up-regulated in tumor cells of different origins. Expression progressively decreased after treatment of tumor cells with retinoic acid.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.; [Isoform 4]: Secreted.

Diseases

Neoplasms
Malignant Neoplasms
Carcinoma
Cytomegalovirus Infections
Ovarian Neoplasm
Liver Carcinoma
Malignant Paraganglionic Neoplasm
Stomach Neoplasms
Melanoma
Uterine Cervical Neoplasm
Malignant Neoplasm Of Larynx

Communicable Diseases
Glioma
Thymoma
Malignant Tumor Of Cervix
Malignant Neoplasm Of Ovary
Colorectal Cancer

Interacting Proteins

KLRK1

Pathways

Cell Death
Immune Response
Secretion

PTMs

Cleavage

Gpi Anchoring

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RAET1E

References

PMID: 14508119 by Conejo-Garcia J.-R., et al. Letal, a tumor-associated NKG2D immunoreceptor ligand, induces activation and expansion of effector immune cells.

PMID: 12732206 by Chalupny N.J., et al. ULBP4 is a novel ligand for human NKG2D.