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- Table of Contents
5 Q&As
Facts about DNA repair protein RAD51 homolog 4.
Part of this Rad21 paralog protein complex BCDX2 which acts from the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruiting and upstream of RAD51 recruitment.
Human | |
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Gene Name: | RAD51D |
Uniprot: | O75771 |
Entrez: | 5892 |
Belongs to: |
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RecA family |
DNA repair protein RAD51 homolog 4; HsTRAD; R51H3Trad; RAD51 homolog D; RAD51DRAD51 (S. cerevisiae)-like 3; RAD51-like 3 (S. cerevisiae); RAD51-like protein 3; recombination repair protein; TRAD
Mass (kDA):
35.049 kDA
Human | |
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Location: | 17q12 |
Sequence: | 17; NC_000017.11 (35092221..35119869, complement) |
Expressed in colon, prostate, spleen, testis, ovary, thymus and small intestine. Weakly expressed in leukocytes.
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, telomere.
PMID: 9512535 by Cartwright R., et al. Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family.
PMID: 9570954 by Pittman D.L., et al. Identification, characterization, and genetic mapping of Rad51d, a new mouse and human RAD51/RecA-related gene.