RAC2 Antibodies

AND RAC2 ELISA kits, RAC2 Proteins

Many biological assays use antibodies to detect RAC2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RAC2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RAC2 antibodies...

We validate the specificity of these antibodies to RAC2 by testing them on tissues known to express RAC2 positively and negatively. Browse below to find the RAC2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RAC2 Infographic by Boster Bio

All RAC2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-RAC2 Antibody

Human, Mouse, Rat

$405
Cat # A01714
100ul

Anti-RAC2 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A01714-1
100ul

Human RAC2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP15153
Starting from 20ug

Anti-RAC2 Antibody (C-term)

Human, Mouse

IF, WB

$299
Cat # M01714
80 µl

RAC2 (NM_002872) Human Over-expression Lysate

Human

$628
Cat # LS005880
100 µg

RAC2 Overview

Facts about Ras-related C3 botulinum toxin substrate 2.

RAC2 3D structure. Source: alphafold

Ras-related C3 botulinum toxin substrate 2 (RAC2)

Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization.

Augments the production of reactive oxygen species (ROS) by NADPH oxidase. .

Gene Information

Human
Gene Name:	RAC2
Uniprot:	P15153
Entrez:	5880

Family

Belongs to:

small GTPase superfamily

Alternative Names

Gx; HSPC022; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP bindingprotein Rac2); rho family, small GTP binding protein Rac2; small GTP-bindingprotein Rac2)

Molecular Weight

Mass (kDA):
21.429 kDA

Genomic Context


Human

Location:	22q13.1
Sequence:	22; NC_000022.11 (37225270..37244269, complement)

Tissue Specificity

Hematopoietic specific.

Subcellular Localizations

Cytoplasm. Membrane-associated when activated.

Diseases

Tissue Adhesions
Inflammation
Leukemia
Malignant Neoplasms
Infective Disorder
Neoplasms
Cell Invasion
Granulomatous Disease, Chronic
Immunologic Deficiency Syndromes
Myeloid Leukemia
Granulomatous Disorder
Myeloid Leukemia, Chronic
Cell Transformation, Neoplastic

Neoplasm Metastasis
Bacterial Infections
Tissue Damage
Innate Immune Response
Lymphoma
Tumor Angiogenesis
Inflammatory Response

Interacting Proteins

PLD2
TNFAIP8L2

Pathways

Chemotaxis
Phagocytosis
Localization
Respiratory Burst
Cell Migration
Cell Adhesion
Immune Response
Neutrophil Chemotaxis
Cell Activation
Cell Growth
Cell Motility
Neutrophil Activation
Exocytosis

Pathogenesis
Cell Proliferation
Virulence
Secretion
Cell Differentiation
Inflammatory Response
Angiogenesis

PTMs

Phosphorylation
Prenylation
Dephosphorylation
Methylation
Ribosylation
Oxidation
Reduction
Cleavage

Geranylgeranylation
Nitrosylation
Glutathionylation
Amidation
Deamidation
Ubiquitination
Farnesylation
Acetylation

Palmitoylation

Research Areas

Signal Transduction
Wnt Signaling Pathway

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RAC2

References

PMID: 2674130 by Didsbury J., et al. Rac, a novel ras-related family of proteins that are botulinum toxin substrates.

PMID: 1316893 by Mizuno T., et al. Regulation of the superoxide-generating NADPH oxidase by a small GTP- binding protein and its stimulatory and inhibitory GDP/GTP exchange proteins.