Rab-like protein 2B Antibodies

AND RABL2B ELISA kits, Rab-like protein 2B Proteins

Many biological assays use antibodies to detect Rab-like protein 2B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Rab-like protein 2B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Rab-like protein 2B antibodies...

We validate the specificity of these antibodies to Rab-like protein 2B by testing them on tissues known to express RABL2B positively and negatively. Browse below to find the RABL2B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: RABL2A

RABL2B Infographic by Boster Bio

All RABL2B Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-RBL2B RABL2B Antibody

Human

ELISA, WB

$380
Cat # A14438
100ul

RABL2B (NM_007081) Human Over-expression Lysate

Human

$628
Cat # LS011158
100 µg

RABL2B Overview

Facts about Rab-like protein 2B.

RABL2B 3D structure. Source: alphafold

Rab-like protein 2B (RABL2B)

Small GTPase required for ciliation. Activated in a guanine nucleotide exchange factor (GEF)-independent manner via its inherent GDP for GTP nucleotide exchange ability (PubMed:28625565).

Involved in ciliary assembly by binding the intraflagellar transport (IFT) complex B in the large pool pre- docked at the bottom of the cilium and thus triggers its entrance to the cilia (PubMed:28625565, PubMed:28428259). .

Gene Information

Human
Gene Name:	RABL2B
Uniprot:	Q9UNT1
Entrez:	11158

Family

Belongs to:

small GTPase superfamily

Alternative Names

FLJ93981; FLJ98216; RAB, member of RAS oncogene family-like 2B; rab-like protein 2B

Molecular Weight

Mass (kDA):
26.101 kDA

Genomic Context


Human

Location:	22q13.33
Sequence:	22; NC_000022.11 (50767500..50783705, complement)

Tissue Specificity

Expressed in the testis.

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm. Localizes on the mother centriole. Localizes slightly apical to the subdistal appendage, but below the distal appendage.

Diseases

Developmental Delay (disorder)
Loss Of Chromosome 22
Muscle Hypotonia
Speech Delay
22q13.3 Deletion Syndrome
Chromosomal Deletion
Liver Diseases
Monosomy
Hepatitis
Hepatitis, Autoimmune
Mild Mental Retardation
Liver Failure

Aneuploidy
Liver Failure, Acute
Virus Diseases
Autoimmune Reaction
Chromosomal Translocation
Neonatal Hypotonia

Pathways

Localization

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RABL2B

References

PMID: 10444334 by Wong A.C., et al. Two novel human RAB genes with near identical sequence each map to a telomere-associated region: the subtelomeric region of 22q13.3 and the ancestral telomere band 2q13.

PMID: 23055941 by Lo J.C., et al. RAB-like 2 has an essential role in male fertility, sperm intra- flagellar transport, and tail assembly.