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- Table of Contents
Facts about Rab GTPase-activating protein 1.
May act as a GTPase-activating protein of RAB6A.
May play a role in microtubule nucleation by centrosome.May participate in a RAB6A-mediated pathway involved in the metaphase- anaphase transition. .
Human | |
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Gene Name: | RABGAP1 |
Uniprot: | Q9Y3P9 |
Entrez: | 23637 |
Belongs to: |
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No superfamily |
DKFZp586D2123; GAP and centrosome-associated protein; GAPCENA; RAB GTPase activating protein 1; rab GTPase-activating protein 1; rab6 GTPase activating protein (GAP and centrosome-associated); Rab6 GTPase activating protein, GAPCenA; Rab6 GTPase-activating protein GAPCenA; RP11-123N4.2; TBC1 domain family, member 11; TBC1D11
Mass (kDA):
121.737 kDA
Human | |
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Location: | 9q33.2-q33.3 |
Sequence: | 9; NC_000009.12 (122931640..123104869) |
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Predominantly cytosolic but also associated with the centrosome.
PMID: 10202141 by Cuif M.-H., et al. Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome.
PMID: 19077034 by Ishibashi K., et al. Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.