Ras-related protein Rab-8B (RAB8B)

The small GTPases Rab are crucial regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.

That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell membranes dynamics in Sertoli cells (By similarity).