This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Ras-related protein Rab-6A.
Has a very low GTPase activity. Involved in COPI-independent retrograde transport from the Golgi to the ER (PubMed:25962623).
Human | |
---|---|
Gene Name: | RAB6A |
Uniprot: | P20340 |
Entrez: | 5870 |
Belongs to: |
---|
small GTPase superfamily |
GTP-binding protein RAB6A'; GTP-binding protein RAB6B; Oncogene RAB6; Rab GTPase; Rab-6; RAB6, member RAS oncogene family; Rab6A variant 3; RAB6A'; RAB6A, member RAS oncogene family; RAB6B; RAB6rab-6; ras-related protein Rab-6A
Mass (kDA):
23.593 kDA
Human | |
---|---|
Location: | 11q13.4 |
Sequence: | 11; NC_000011.10 (73675638..73761074, complement) |
Ubiquitous.
Golgi apparatus membrane; Lipid-anchor. BICD2 facilitates its targeting to Golgi apparatus membrane.; [Isoform 1]: Golgi apparatus membrane; Lipid-anchor.; [Isoform 2]: Golgi apparatus membrane; Lipid-anchor.
PMID: 2501306 by Zahraoui A., et al. The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.
PMID: 10996854 by Caillol N., et al. Impairment of bile salt-dependent lipase secretion in human pancreatic tumoral SOJ-6 cells.