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- Table of Contents
Facts about Rab3 GTPase-activating protein non-catalytic subunit.
Rab3 GTPase-activating complex especially converts active Rab3-GTP into the inactive form Rab3- GDP. Required for normal eye and brain development.
Human | |
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Gene Name: | RAB3GAP2 |
Uniprot: | Q9H2M9 |
Entrez: | 25782 |
Belongs to: |
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Rab3-GAP regulatory subunit family |
DKFZP434D245; FLJ14579; KIAA0839p150; RAB3 GTPase activating protein subunit 2 (non-catalytic); Rab3 GTPase-activating protein 150 kDa subunit; rab3 GTPase-activating protein non-catalytic subunit; Rab3-GAP p150; Rab3-GAP regulatory subunit; RAB3GAP150; RAB3-GAP150; RGAP-iso
Mass (kDA):
155.985 kDA
Human | |
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Location: | 1q41 |
Sequence: | 1; NC_000001.11 (220148293..220272453, complement) |
Ubiquitous.
Cytoplasm. In neurons, it is enriched in the synaptic soluble fraction.
PMID: 9733780 by Nagano F., et al. Molecular cloning and characterization of the noncatalytic subunit of the Rab3 subfamily-specific GTPase-activating protein.
PMID: 22337587 by Haines D.S., et al. Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking.