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- Table of Contents
Facts about Rab11 family-interacting protein 4.
In case of disease by HCMV (human cytomegalovirus), may participate in egress of the virus from nucleus; this function is independent of ARF6. .
Human | |
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Gene Name: | RAB11FIP4 |
Uniprot: | Q86YS3 |
Entrez: | 84440 |
Belongs to: |
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No superfamily |
ARFO2; Arfophilin-2; FIP4-Rab11; FLJ00131; KIAA1821arfophilin-2; MGC11316; MGC126566; RAB11 family interacting protein 4 (class II); rab11 family-interacting protein 4; RAB11-FIP4
Mass (kDA):
71.928 kDA
Human | |
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Location: | 17q11.2 |
Sequence: | 17; NC_000017.11 (31391675..31538211) |
Present at high level in testis (at protein level). Weakly expressed in other tissues.
Endosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Recycling endosome membrane; Peripheral membrane protein. Cleavage furrow. Midbody. Cytoplasmic vesicle. Recruited to the cleavage furrow and the midbody during cytokinesis.
PMID: 12470645 by Wallace D.M., et al. Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells.
PMID: 12696059 by Jenne D.E., et al. Complete physical map and gene content of the human NF1 tumor suppressor region in human and mouse.