Sulfhydryl oxidase 2 Antibodies

AND QSOX2 ELISA kits, Sulfhydryl oxidase 2 Proteins

Many biological assays use antibodies to detect Sulfhydryl oxidase 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sulfhydryl oxidase 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sulfhydryl oxidase 2 antibodies...

We validate the specificity of these antibodies to Sulfhydryl oxidase 2 by testing them on tissues known to express QSOX2 positively and negatively. Browse below to find the QSOX2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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QSOX2 Infographic by Boster Bio

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Anti-QSOX2 Antibody Picoband®

Human

ELISA, IF, IHC, ICC, WB

$370
Cat # A10205-1
100 μg/vial

QSOX2 Overview

Facts about Sulfhydryl oxidase 2.

QSOX2 3D structure. Source: alphafold

Sulfhydryl oxidase 2 (QSOX2)

Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the decrease of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in many different secreted proteins.

Also seems to play a part in regulating the sensitization of neuroblastoma cells for interferon-gamma-induced apoptosis. .

Gene Information

Human
Gene Name:	QSOX2
Uniprot:	Q6ZRP7
Entrez:	169714

Family

Belongs to:

quiescin-sulfhydryl oxidase (QSOX) family

Alternative Names

DKFZp762A2013; quiescin Q6 sulfhydryl oxidase 2; quiescin Q6-like 1; quiescin Q6-like protein 1

Molecular Weight

Mass (kDA):
77.529 kDA

Genomic Context


Human

Location:	9q34.3
Sequence:	9; NC_000009.12 (136206333..136245812, complement)

Tissue Specificity

Expressed in pancreas, brain, placenta, kidney, heart and fetal tissues. Weakly expressed in lung, liver and skeletal muscles.

Subcellular Localizations

Membrane; Single-pass membrane protein. Secreted. Cell membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Seems to be predominantly targeted to the nuclear and outer plasma membrane.

Diseases

Neuroblastoma
Complete Hearing Loss
Tumor Angiogenesis
Dental Plaque
Sensorineural Hearing Loss (disorder)
Atheroma

Atherosclerosis

Pathways

Cell Activation
Sensitization
Induction Of Apoptosis
Cell Death
Protein Folding
Cell Differentiation
Angiogenesis

Secretion

PTMs

Disulfide bond

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/QSOX2

References

PMID: 14633699 by Wittke I., et al. Neuroblastoma-derived sulfhydryl oxidase, a new member of the sulfhydryl oxidase/quiescin 6 family, regulates sensitization to interferon gamma-induced cell death in human neuroblastoma cells.