QPRT Antibodies

AND QPRT ELISA kits, QPRT Proteins

Many biological assays use antibodies to detect QPRT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with QPRT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop QPRT antibodies...

We validate the specificity of these antibodies to QPRT by testing them on tissues known to express QPRT positively and negatively. Browse below to find the QPRT antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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QPRT Infographic by Boster Bio

All QPRT Products

Product

Figures

Specificity

Applications

Price

Human QPRT Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ15274
Starting from 20ug

Anti-QPRT Mouse Monoclonal Antibody [Clone ID: OTI1C10]

+10

Human

Flow Cytometry, IF, IHC, WB

$523
Cat # M09896
100 µl

QPRT (NM_014298) Human Over-expression Lysate

Human

$628
Cat # LS023475
100 µg

Anti-QPRT Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A09896
100 µg/vial

QPRT Overview

Facts about Nicotinate-nucleotide pyrophosphorylase [carboxylating].

QPRT 3D structure. Source: alphafold

Nicotinate-nucleotide pyrophosphorylase [carboxylating] (QPRT)

Involved in the catabolism of quinolinic acid (QA). .

Gene Information

Human
Gene Name:	QPRT
Uniprot:	Q15274
Entrez:	23475

Family

Belongs to:

NadC/ModD family

Alternative Names

EC 2.4.2.19; nicotinate-nucleotide pyrophosphorylase (carboxylating); QAPRTase; QPRTasenicotinate-nucleotide pyrophosphorylase [carboxylating]; Quinolinate phosphoribosyltransferase [decarboxylating]; quinolinate phosphoribosyltransferase

Molecular Weight

Mass (kDA):
30.846 kDA

Genomic Context


Human

Location:	16p11.2
Sequence:	16; NC_000016.10 (29670588..29698699)

Diseases

Neurodegenerative Disorders
Epilepsy
Huntington Disease
Nervousness
Schizophrenia
Diabetes Mellitus
Adenoma
Partial Seizure
Quadriparesis
Pellagra
Carcinoma

Follicular Adenoma
Thyroid Gland Follicular Adenoma
Premenstrual Tension
Microcephaly
Follicular Thyroid Carcinoma
Nerve Degeneration

Pathways

Localization
Pathogenesis
Cellular Localization
Cell Death
Excretion

PTMs

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/QPRT

References

PMID: 9473669 by Fukuoka S., et al. Characterization and functional expression of the cDNA encoding human brain quinolinate phosphoribosyltransferase.

PMID: 17868694 by Liu H., et al. Structural and kinetic characterization of quinolinate phosphoribosyltransferase (hQPRTase) from homo sapiens.