Peptide YY Antibodies

Peptide YY (PYY)

This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. .

Gene Information

Human
Gene Name:	PYY
Uniprot:	P10082
Entrez:	5697

Family

Belongs to:
NPY family

Alternative Names

Peptide tyrosine tyrosine; Peptide YY; Peptide-YY; PYY; PYY1; PYY-I

Molecular Weight

Mass (kDA):
11.145 kDA

Genomic Context

Human
Location:	17q21.31
Sequence:	17; NC_000017.11 (43952733..44004469, complement)

Subcellular Localizations

Secreted.

Diseases

• Obesity
• Nervousness
• Diabetes Mellitus
• Neoplasms
• Insulin Resistance
• Diabetes Mellitus, Non-insulin-dependent
• Pathologic Vasoconstriction
• Obesity, Morbid
• Malignant Neoplasms
• Hyperphagia
• Hereditary Pyropoikilocytosis

• Pituitary Diseases
• Insulin Sensitivity
• Diarrhea
• Pathologic Fistula
• Inflammation
• Pertussis

Interacting Proteins

• NPY1R
• NPY2R

Pathways

• Secretion
• Gastric Emptying
• Localization
• Energy Homeostasis
• Acid Secretion
• Insulin Secretion
• Vasoconstriction
• Transport
• Gastric Acid Secretion
• Glucose Homeostasis
• Hormone Secretion
• Feeding Behavior
• Pathogenesis

• Innervation
• Response To Food
• Cell Growth
• Regulation Of Appetite
• Eating Behavior
• Cell Proliferation
• Peptide Secretion

PTMs

• Acylation
• Amidation
• Cleavage
• Phosphorylation
• Iodination
• Oxidation
• Hydroxylation

• Biotinylation
• Reduction
• Glycosylation
• Decarboxylation
• Deamidation
• Methylation
• Palmitoylation

• Deglycosylation

Research Areas

• Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PYY

Boster Bio - Best Uses Of The PYY Marker

If you're a biologist or a researcher, you're probably wondering if Boster Bio's Anti-PYY Marker is right for your research. The company's product is a monoclonal antibody that recognizes the CD68 marker on macrophages. Here's why this antibody is so effective in the lab. Continue reading to learn even more.

Boster Bio Anti -CD68 Monoclonal Antibody

This antibody recognizes the glycoprotein CD68, a 110-kDa integral membrane glycoprotein, which is important for macrophage identification in tissue sections. It also reacts well with myeloid precursors. Peripheral blood granulocytes. Plasmacytoid T cells. These cells are thought to have monocyte/macrophage origin. It has been used to perform immunohistochemistry, and Immunofluorescence studies.

Its eBioY1/82A antigen is suitable to intracellular and surface staining for B cells. This antibody has been validated and is compatible to flow cytometric analysis. Typically, 105 to108 cells will be stained using one-half of to one-mL of diluted solution. It is important to determine the number and type of cells that will be stained before you use this antibody.

Tumor-associated macrophages are divided into two main subtypes - M1 and M2. M1 macrophages are inhibitory of tumor growth and metastasis. M2 macrophages promote tumor development and metastasis. This study investigated the mechanisms of this M2-macrophage-dominant tumor microenvironment.

The monoclonal antibodies have many applications. In immunohistochemistry, it can be used to detect Mph. It can be used to detect FB or PGM1 macrophages. They share the same markers. It has a high affinity for Mph, which will enable it to identify these two cell types. Boster Bio Anti CD68 monoclonal Antibody Monoclonal Antibody from Boster Bio may be used in diagnostic tests to improve accuracy.

IL-17 plays a critical role in tumors. It recruits macrophages through the increase in expression of IL-17 and PGE2 receptors. Increased levels of IL-17 may recruit monocytes into the tumor microenvironment. Monoclonal antibodies can also be used to enhance tumor growth by inhibiting the migration of M2 macrophages.

Boster Bio Anti-Peptide YY/PYY Antibody

Boster Bio Antipeptidide yY/PYY Antibody was developed to recognize the PYY mark. It is a phosphorylated marker which labels cells that secrete enteroglucagon. The PYY signal is only found in L cells. This antibody detects all 93 L-cells for PYY.

Boster Bio Anti-CD68

The Boster bio Anti-CD68 Monoclonal Antibody (Macrophage Marker), is a safe, non-hazardous antibody that can be used in IHC applications. It is available without BSA. The price for blocking peptides is 1.0 mg/ml. The antibodies are tested against known positive or negative samples. Boster Bio's commitment towards quality and service ensures these results.

This antibody targets protein peptide (YY) and is highly specific. These antibodies are available from many suppliers. Visit the product information pages to learn more about their operation. Each product page contains detailed information on the use of the antibodies. Here are some of Boster bio Anti-CD68's most commonly used applications. Here are some of the benefits this antibody offers. It is highly sensitive and accurate when used correctly.