PTPN4 Antibodies

AND PTPN4 ELISA kits, PTPN4 Proteins

Many biological assays use antibodies to detect PTPN4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTPN4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTPN4 antibodies...

We validate the specificity of these antibodies to PTPN4 by testing them on tissues known to express PTPN4 positively and negatively. Browse below to find the PTPN4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTPN4 Infographic by Boster Bio

All PTPN4 Products

Product

Figures

Specificity

Applications

Price

Human PTPN4 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTP29074
Starting from 20ug

MEG1 (PTPN4) (NM_002830) Human Over-expression Lysate

Human

$628
Cat # LS005775
100 µg

PTPN4 Overview

Facts about Tyrosine-protein phosphatase non-receptor type 4.

PTPN4 3D structure. Source: alphafold

Tyrosine-protein phosphatase non-receptor type 4 (PTPN4)

May behave at junctions between the membrane and the cytoskeleton. .

Gene Information

Human
Gene Name:	PTPN4
Uniprot:	P29074
Entrez:	5775

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

EC 3.1.3.48; MEG; megakaryocyte phosphatase; megakaryocyte protein-tyrosine phosphatase; protein tyrosine phosphatase MEG1; protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte); Protein-tyrosine phosphatase MEG1; PTPase-MEG1; PTPMEG; PTPMEG1; tyrosine-protein phosphatase non-receptor type 4

Molecular Weight

Mass (kDA):
105.911 kDA

Genomic Context


Human

Location:	2q14.2
Sequence:	2; NC_000002.12 (119759922..119984899)

Subcellular Localizations

Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cytoplasm.

Diseases

Rabies (disorder)
Posttransfusion Purpura
Stomach Neoplasms
Adenocarcinoma
Gastric Adenocarcinoma
Malignant Neoplasm Of Stomach
Malignant Neoplasms
Nervousness

Glioblastoma
Osteoporosis
Colorectal Cancer

Interacting Proteins

CRK
KAT5
MAPK12
NCK1

Pathways

Cell Development
Protein Phosphorylation
Cell Activation
T Cell Differentiation
Cell-cell Signaling
Cell Death
T Cell Activation
Cell Differentiation
Cytokine Secretion

Virulence
Bone Resorption
Secretion

PTMs

Dephosphorylation

Phosphorylation

Oxidation

Research Areas

Protein Phosphatase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTPN4

References

PMID: 1648233 by Gu M., et al. Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1.

PMID: 8483328 by Honda H., et al. Identification of novel protein-tyrosine phosphatases in a human leukemia cell line, F-36P.