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- Table of Contents
Facts about Serine/threonine-protein phosphatase 1 regulatory subunit 10.
Mediates discussion of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities.
Human | |
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Gene Name: | PPP1R10 |
Uniprot: | Q96QC0 |
Entrez: | 5514 |
Belongs to: |
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No superfamily |
CAT53; FB19PP1-binding protein of 114 kDa; MHC class I region proline-rich protein CAT53; p99; Phosphatase 1 nuclear targeting subunit; phosphatase nuclear targeting subunit; PNUTS; PNUTSPP1R10; PPP1R10; Protein FB19; protein phosphatase 1 regulatory subunit 10; protein phosphatase 1, regulatory (inhibitor) subunit 10; protein phosphatase 1, regulatory subunit 10; serine/threonine-protein phosphatase 1 regulatory subunit 10
Mass (kDA):
99.058 kDA
Human | |
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Location: | 6p21.33 |
Sequence: | 6; NC_000006.12 (30600400..30618607, complement) |
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Nucleus. Found in discrete nucleoplasmic bodies and within nucleoli. Associates with chromatin during interphase, excluded from condensed chromosomes during early mitosis and is reloaded onto chromosomes at the late telophase (By similarity).
PMID: 9784381 by Totaro A., et al. Cloning of a new gene (FB19) within HLA class I region.
PMID: 9450550 by Kreivi J.P., et al. Purification and characterisation of p99, a nuclear modulator of protein phosphatase 1 activity.