Platelet basic protein Antibodies

Platelet basic protein (PPBP)

LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. Additionally, it stimulates the formation and secretion of plasminogen activator by human synovial cells.

NAP-2 is a ligand for both CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and many potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules.

Gene Information

Human
Gene Name:	PPBP
Uniprot:	P02775
Entrez:	5473

Family

Belongs to:
intercrine alpha (chemokine CxC) family

Alternative Names

Beta-TG; connective tissue-activating peptide III; CTAP III; CTAP3CTAP-III; CTAPIII; CXC chemokine ligand 7; C-X-C motif chemokine 7; CXCL7; CXCL7b-TG1; LA-PF4; LDGFTC1; Leukocyte-derived growth factor; low-affinity platelet factor IV; Macrophage-derived growth factor; MDGFTC2; NAP2; NAP-2; NAP-2-L1; neutrophil-activating peptide 2; neutrophil-activating peptide-2; PBPTHBGB; platelet basic protein; PPBP; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7); SCAR10; SCYB7beta-thromboglobulin; small inducible cytokine B7; small inducible cytokine subfamily B, member 7; Small-inducible c

Molecular Weight

Mass (kDA):
13.894 kDA

Genomic Context

Human
Location:	4q13.3
Sequence:	4; NC_000004.12 (73986439..73988190, complement)

Subcellular Localizations

Secreted.

Diseases

• Inflammation
• Endocarditis
• Melanoma
• Infective Disorder
• Bacteremia
• Infarction
• Staphylococcal Infections
• Ischemia
• Bacterial Endocarditis
• Arterial Occlusion
• Occlusion, Middle Cerebral Artery
• Cerebral Artery Occlusion

• Infective Endocarditis
• Brain Ischemia
• Pertussis
• Malignant Neoplasms
• Inflammatory Response
• Tissue Adhesions
• Cerebrovascular Accident

Interacting Proteins

• CCL5
• CXCL9

Pathways

• Chemotaxis
• Pathogenesis
• Neuroprotection
• Secretion
• Neutrophil Chemotaxis
• Platelet Activation
• Neutrophil Activation
• Cell Activation
• Inflammatory Response
• Neutrophil Degranulation
• Cell Death
• Exocytosis
• Proteolysis

• Localization
• Angiogenesis
• Cell Adhesion
• Basophil Activation
• Virulence
• Wound Healing
• Acute Inflammatory Response

PTMs

• Cleavage
• Phosphorylation
• Formylation

• Glycosylation
• Dephosphorylation
• Deglycosylation

• Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPBP

Best Uses Of The PPBP Marker From Boster Bio

Boster Bio's AntiNAP2/PPBP marker the first component of the patented PPBP Protein. These two proteins work together to prevent the formation of the apoptosis gene (a cause of disease). This article will explain the roles of both markers. The guide also gives tips on how to optimize and troubleshoot experiments. This guide will help you eliminate several possible error causes.

Boster Bio's Anti-NAP2/PPBP Marker

Anti-NAP2/PPBP, a monoclonal antibody that has been tested for IHC-P, flow cytometry, and ICC is a new one. It is a powerful tool to analyze lymphatic markers. The chromatographic methods that are proprietary to extract the recombinant MVP proteins were employed. It can be stored at room temperature for up to 3 weeks. It is best to keep it at a temperature of less than -18°C.

Optimization guides help eliminate a number possible causes of error

While the Boster Bio guide will provide you with the best results, you might run into some issues while conducting your study. For example, the protocol for sample preparation might be incorrect. Boster Bio optimization guides can prevent this from happening. The guide will also provide detailed troubleshooting tips. To determine the optimal concentration of antibodies, you'll have to conduct an antibody titration experiment. Boster Bio's guide will outline the minimum concentration required for the highest signal.

Troubleshooting guides can help you eliminate the many possible causes of error.

Troubleshooting is the process of identifying and eliminating an issue. It is a systematic process that is used to fix complicated electronic devices, machines and software systems. It is a useful device for computer users who are experiencing problems with a particular application or system. The first step is to gather information regarding the issue. Then, you can eliminate any components that are unnecessary. This will help find out if there are incompatibilities or products from third parties that could lead to problems.

Troubleshooting guides often include an inventory of possible causes to help pinpoint the problem. This helps users quickly identify the most common errors. When using the PPBP marker, troubleshooting guides can help get rid of a lot of error-causing causes. If you have a problem that is repeated troubleshooting guides can help you prevent it from occurring again.