POLR2C Antibodies

AND POLR2C ELISA kits, POLR2C Proteins

Many biological assays use antibodies to detect POLR2C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POLR2C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POLR2C antibodies...

We validate the specificity of these antibodies to POLR2C by testing them on tissues known to express POLR2C positively and negatively. Browse below to find the POLR2C antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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POLR2C Infographic by Boster Bio

All POLR2C Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-POLR2C Antibody

Human, Mouse

IP, WB

$405
Cat # A09308
100ul

Human POLR2C Recombinant Protein

SDS-PAGE

$250
Cat # PROTP19387
Starting from 20ug

Anti-POLR2C Antibody (C-term)

Human, Mouse

IF, IHC-P, WB

$299
Cat # A09308-1
80 µl

Anti-POLR2C Rabbit Monoclonal Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # M09308
100 μl/vial

POLR2C (NM_032940) Human Over-expression Lysate

Human

$628
Cat # LS005432
100 µg

POLR2C Overview

Facts about DNA-directed RNA polymerase II subunit RPB3.

POLR2C 3D structure. Source: alphafold

DNA-directed RNA polymerase II subunit RPB3 (POLR2C)

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.

Pol II is the central part of the basal RNA polymerase II transcription machinery. It's composed of cellular elements that move relative to each other.

Gene Information

Human
Gene Name:	POLR2C
Uniprot:	P19387
Entrez:	5432

Family

Belongs to:

archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family

Alternative Names

DNA-directed RNA polymerase II 33 kDa polypeptide; DNA-directed RNA polymerase II subunit C; DNA-directed RNA polymerase II subunit RPB3; hRPB33; hsRPB3; polymerase (RNA) II (DNA directed) polypeptide C (33kD); polymerase (RNA) II (DNA directed) polypeptide C, 33kDa; RNA polymerase II subunit 3; RNA polymerase II subunit B3; RPB3; RPB31; RPB33

Molecular Weight

Mass (kDA):
31.441 kDA

Genomic Context


Human

Location:	16q21
Sequence:	16; NC_000016.10 (57462679..57472009)

Subcellular Localizations

Nucleus.

Diseases

Colonic Neoplasms
Neoplasm Metastasis
Psoriasis
Malignant Neoplasms
Colorectal Neoplasms
Colorectal Cancer Metastatic
Colorectal Cancer
Rectal Neoplasms

Lymphohistiocytosis, Hemophagocytic
Metabolic Bone Disorder
Carcinoma

Interacting Proteins

ATF4

Pathways

Localization
Myoblast Proliferation
Dna Repair
Cell Growth
Rna Interference
Nuclear Import

PTMs

Phosphoprotein

Research Areas

DNA Repair
DNA replication, Transcription, Translation and Splicing

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POLR2C

References

PMID: 2187864 by Pati U.K., et al. The amino acid sequence of the human RNA polymerase II 33-kDa subunit hRPB 33 is highly conserved among eukaryotes.

PMID: 9540830 by Dammann R., et al. Cloning and characterization of the human RNA polymerase I subunit hRPA40.