PLA2G10 Antibodies

AND PLA2G10 ELISA kits, PLA2G10 Proteins

Many biological assays use antibodies to detect PLA2G10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PLA2G10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PLA2G10 antibodies...

We validate the specificity of these antibodies to PLA2G10 by testing them on tissues known to express PLA2G10 positively and negatively. Browse below to find the PLA2G10 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLA2G10 Infographic by Boster Bio

All PLA2G10 Products

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Price

PLA2G10 Secreted Phospholipase A2-X Human Recombinant Protein

Human

$250
Cat # PROTO15496
2ug, 10ug, 1mg

PLA2G10 (NM_003561) Human Over-expression Lysate

Human

$628
Cat # LS008399
100 µg

PLA2G10 Overview

Facts about Group 10 secretory phospholipase A2.

PLA2G10 3D structure. Source: alphafold

Group 10 secretory phospholipase A2 (PLA2G10)

PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Has a strong potency for releasing arachidonic acid from cell membrane phospholipids.

Prefers phosphatidylethanolamine and phosphatidylcholine liposomes to those of phosphatidylserine. .

Gene Information

Human
Gene Name:	PLA2G10
Uniprot:	O15496
Entrez:	8399

Family

Belongs to:

phospholipase A2 family

Alternative Names

EC 3.1.1.4; group 10 secretory phospholipase A2; Group X secretory phospholipase A2; GX sPLA2; GXPLA2; GXSPLA2; MGC119918; MGC119919; MGC133367; Phosphatidylcholine 2-acylhydrolase 10; phospholipase A2, group X; SPLA2; sPLA2-X

Molecular Weight

Mass (kDA):
18.153 kDA

Genomic Context


Human

Location:	16p13.12
Sequence:	16; NC_000016.10 (14672548..14694662, complement)

Tissue Specificity

Found in spleen, thymus, peripheral blood leukocytes, pancreas, lung, and colon.

Subcellular Localizations

Secreted.

Diseases

Inflammation
Atherosclerosis
Metaplasia
Malignant Neoplasms
Neoplasms
Asthma
Aneurysm
Carcinoma
Adenocarcinoma
Aortic Aneurysm
Aortic Aneurysm, Abdominal
Infarction
Colonic Neoplasms

Myocardial Infarction
Colorectal Cancer
Endotoxic Shock
Arteriosclerosis
Stomach Neoplasms
Malignant Tumor Of Colon
Lung Diseases

Interacting Proteins

INCA1
WDYHV1

Pathways

Secretion
Pathogenesis
Cell Proliferation
Localization
Transport
Histone Deacetylation
Fertilization
Proteolysis
Pigmentation
Respiratory Burst
Cell Cycle Arrest
Cell Maturation
Lipoprotein Modification

Sperm Motility
Phagocytosis
Acrosome Reaction
Cholesterol Efflux
Cell Cycle
Reverse Cholesterol Transport
Cholesterol Transport

PTMs

Sumoylation
Phosphorylation

Deacetylation
Oxidation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLA2G10

References

PMID: 9188469 by Cupillard L., et al. Cloning, chromosomal mapping, and expression of a novel human secretory phospholipase A2.

PMID: 12161451 by Pan Y.H., et al. Crystal structure of human group X secreted phospholipase A2. Electrostatically neutral interfacial surface targets zwitterionic membranes.