Pirin Antibodies

AND PIR ELISA kits, Pirin Proteins

Many biological assays use antibodies to detect Pirin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pirin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pirin antibodies...

We validate the specificity of these antibodies to Pirin by testing them on tissues known to express PIR positively and negatively. Browse below to find the PIR antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PIR Infographic by Boster Bio

All PIR Products

Product

Figures

Specificity

Applications

Price

Pirin (PIR) (NM_001018109) Human Recombinant Protein

$1249
Cat # PROTO00625
20 µg

Pirin (PIR) (NM_003662) Human Over-expression Lysate

Human

$628
Cat # LS008544
100 µg

Anti-PIR Antibody Picoband™

Human, Monkey, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A03468-1
100 µg/vial

PIR Overview

Facts about Pirin.

PIR 3D structure. Source: alphafold

Pirin (PIR)

Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent method. May be required for efficient terminal myeloid maturation of hematopoietic cells.

Has quercetin 2,3-dioxygenase activity (in vitro). .

Gene Information

Human
Gene Name:	PIR
Uniprot:	O00625
Entrez:	8544

Family

Belongs to:

pirin family

Alternative Names

EC 1.13.11.24; pirin (iron-binding nuclear protein); pirin; Probable quercetin 2,3-dioxygenase PIR; Probable quercetinase

Molecular Weight

Mass (kDA):
32.113 kDA

Genomic Context


Human

Location:	Xp22.2
Sequence:	X; NC_000023.11 (15384799..15493588, complement)

Tissue Specificity

Highly expressed in a subset of melanomas. Detected at very low levels in most tissues (at protein level). Expressed in all tissues, with highest level of expression in heart and liver.

Subcellular Localizations

Nucleus. Cytoplasm. Predominantly localized in dot-like subnuclear structures. Cytoplasmic localization of PIR seems to positively correlate with melanoma progression.