Protein piccolo Antibodies

AND Pclo ELISA kits, Protein piccolo Proteins

Many biological assays use antibodies to detect Protein piccolo, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein piccolo in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein piccolo antibodies...

We validate the specificity of these antibodies to Protein piccolo by testing them on tissues known to express Pclo positively and negatively. Browse below to find the Pclo antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Pclo Infographic by Boster Bio

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Anti-Piccolo Monoclonal Antibody

3 Q&As

Human, Mouse, Rat

ELISA, IF, ICC, WB

$415
Cat # M05881
100ug

Pclo Overview

Facts about Protein piccolo.

Protein piccolo (Pclo)

May act as a scaffolding protein involved in the organization of synaptic active zones and in synaptic vesicle trafficking. .

Gene Information

Mouse
Gene Name:	Pclo
Uniprot:	Q9QYX7
Entrez:	26875

Family

Belongs to:

No superfamily

Alternative Names

ACZ; Aczonin; PCLO; piccolo (presynaptic cytomatrix protein); Piccolo; protein piccolo

Molecular Weight

Mass (kDA):
550.834 kDA

Genomic Context


Mouse

Location:	5\|5 A1
Sequence:	5;

Tissue Specificity

Highly expressed in brain. Moderately expressed in pituitary gland and pancreatic islets. Low levels found in stomach.

Diseases

Major Depressive Disorder
Depressive Disorder
Schizophrenia
Mental Disorders
Bipolar Disorder
Neoplasms
Diabetes Mellitus
Impairment (finding)
Impaired Cognition
Mood Disorders
Nervousness
Autistic Disorder

Cholangiocarcinoma
Learning Disorders
Malnutrition
Varicosity
Headache
Pituitary Diseases

Pathways

Exocytosis
Transport
Localization
Secretion
Insulin Secretion
Synaptic Transmission
Endocytosis
Dopamine Uptake
Sensitization
Synaptic Vesicle Exocytosis
Synapse Maturation
Clathrin-mediated Endocytosis
Intracellular Transport

Brain Development
Vesicle Docking
Vesicle Fusion
Synaptic Vesicle Clustering
Cell Death
Synaptic Vesicle Fusion
Synapse Assembly

PTMs

Prenylation

Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Pclo

References

PMID: 10508862 by Wang X., et al. Aczonin, a 550-kd putative scaffolding protein of presynaptic active zones, shares homology regions with rim and bassoon and binds profilin.

PMID: 12401793 by Fujimoto K., et al. Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP- GEFII.Rim2.Piccolo complex in cAMP-dependent exocytosis.