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Poliovirus receptor Antibodies
AND PVR ELISA kits, Poliovirus receptor Proteins
Many biological assays use antibodies to detect Poliovirus receptor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Poliovirus receptor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Poliovirus receptor antibodies...
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PVR Infographic by Boster Bio
All PVR Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK1831
96 wells/kit, with removable strips.
Cat # EK1831
96 wells/kit, with removable strips.
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00664-2
100 μg/vial
Cat # A00664-2
100 μg/vial
Human
ELISA, IF, IHC, ICC, WB
$370
Cat # A00664-4
100 μg/vial
Cat # A00664-4
100 μg/vial
Human, Mouse
IHC, WB
$370
Cat # M00664-1
100 μg/vial
Cat # M00664-1
100 μg/vial
Human, Mouse
Flow Cytometry, IHC, WB
$370
Cat # M00664-2
100 μg/vial
Cat # M00664-2
100 μg/vial
Human, Mouse
Flow Cytometry, IHC, WB
$370
Cat # M00664-3
100 μg/vial
Cat # M00664-3
100 μg/vial
PVR Overview
Facts about Poliovirus receptor.
Poliovirus receptor (PVR)
Mediates NK cell adhesion and triggers NK cell effector functions. Binds two distinct NK cell receptors: CD96 and CD226.
These interactions accumulates at the cell-cell contact site, leading to the creation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and trigger cytoxicity of activated NK cells.
Gene Information
| Human | |
|---|---|
| Gene Name: | PVR |
| Uniprot: | P15151 |
| Entrez: | 5817 |
Family
| Belongs to: |
|---|
| nectin family |
Alternative Names
CD155 antigen; CD155; HVED; NECL5; Necl-5; nectin-like 5; Nectin-like protein 5; poliovirus receptor; PVR; PVS; PVSFLJ25946; Tage4
Molecular Weight
Mass (kDA):
45.303 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.31 |
| Sequence: | 19; NC_000019.10 (44643798..44666162) |
Subcellular Localizations
[Isoform Alpha]: Cell membrane; Single-pass type I membrane protein.; [Isoform Delta]: Cell membrane; Single-pass type I membrane protein.; [Isoform Beta]: Secreted.; [Isoform Gamma]: Secreted.
Diseases
- Hypertensive Disease
- Pulmonary Hypertension
- Proliferative Vitreoretinopathy
- Retinal Detachment
- Pathologic Vasoconstriction
- Hypoxia
- Prostatic Hyperplasia
- Heart Failure
- Benign Prostatic Hypertrophy
- Hyperplasia
- Anoxia
- Cerebrovascular Accident
- Idiopathic Pulmonary Hypertension
Interacting Proteins
- KRTAP10-7
- KRTAP10-8
- KRTAP10-9
- NOTCH2NL
- SLC30A2
- TIGIT
Pathways
- Vasoconstriction
- Vasodilation
- Pathogenesis
- Cell Proliferation
- Cell Migration
- Micturition
- Coagulation
- Transport
- Cell Adhesion
- Enucleation
- Localization
- Response To Hypoxia
- Wound Healing
PTMs
- Phosphorylation
- Nitration
- Oxidation
- Glycosylation
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PVR
bosterbio.com/bosterbio-gene-info-cards/PVR
References
PMID: 2538245 by Mendelsohn C.L., et al. Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily.
PMID: 2170108 by Koike S., et al. The poliovirus receptor protein is produced both as membrane-bound and secreted forms.