PTPRN Antibodies

AND PTPRN ELISA kits, PTPRN Proteins

Many biological assays use antibodies to detect PTPRN, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTPRN in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTPRN antibodies...

We validate the specificity of these antibodies to PTPRN by testing them on tissues known to express PTPRN positively and negatively. Browse below to find the PTPRN antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTPRN Infographic by Boster Bio

All PTPRN Products

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Product

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Specificity

Applications

Price

Anti-PTPRN Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A03116
100ul

PTPRN (NM_002846) Human Over-expression Lysate

Human

$960
Cat # LS005798
100 µg

PTPRN Overview

Facts about Receptor-type tyrosine-protein phosphatase-like N.

PTPRN 3D structure. Source: alphafold

Receptor-type tyrosine-protein phosphatase-like N (PTPRN)

Plays a role in vesicle-mediated secretory processes (PubMed:24843546). Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets (By similarity).

Required for the accumulation of normal levels of insulin-containing vesicles and preventing their degradation (PubMed:24843546). Plays a role in insulin secretion in response to glucose stimuli (PubMed:24843546).

Gene Information

Human
Gene Name:	PTPRN
Uniprot:	Q16849
Entrez:	5798

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

CA 512; EC 3.1.3.48; FLJ16131; IA2; IA-2; IA-2/PTP; ICA 512; ICA3; ICA512; islet cell antigen 2; Islet cell antigen 512; Islet cell autoantigen 3; protein tyrosine phosphatase, receptor type, N; protein tyrosine phosphatase-like N; PTP IA-2; PTPRN; receptor-type tyrosine-protein phosphatase-like N; R-PTP-N

Molecular Weight

Mass (kDA):
105.848 kDA

Genomic Context


Human

Location:	2q35
Sequence:	2; NC_000002.12 (219289623..219309404, complement)

Tissue Specificity

Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary.

Subcellular Localizations

Membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type I membrane protein. Perikaryon. Cell projection, axon. Cell junction, synapse. Cell membrane; Single-pass type I membrane protein. Endosome. Detected on neuronal secretory vesicles, but not on synaptic vesicles. Colocalizes with insulin-containing secretory granules (PubMed:25561468). Primarily detected on secretory vesicle membranes. Transiently found at the cell membrane, when secretory vesicles fuse with the cell membrane to release their cargo. Is then endocytosed and recycled t